CAJ | 학술논문

目的：探讨云南漾濞彝族族群HLA-DQA1频率分布特征，并与华人19个群体比较。方法：采用限制性片段长度多态性分析（PCR-RFLP）方法。结果： DQA1*0301(31.63％)最高，*0401(1.0 2％)最低。卡方总体检验表明，该族群与北方六个汉人群体、满族、新加坡群体及新疆维吾尔族无显著差异(P>0.05),但有个别基因频率的显著差异；布依族、傣族、台湾群体组成复杂, 与其他群体有很大显著差异（P>0.001)；广东汉人与广西壮族与其他群体也有极其显著的差异；哈萨克族与维吾尔族相似；维吾尔族与部分北方汉族并无显著差异；藏族与哈萨克族、新加坡群体无显著差异。结论：南方各族群DQA1的复杂构成，可能与起源的多样性或地域环境有关。漾濞彝族族群HLA-DQA1构成有北方族群特征。
목적：탐토운남양비이족족군HLA-DQA1빈솔분포특정，병여화인19개군체비교。방법：채용한 제성편단장도다태성분석（PCR-RFLP）방법。결과： DQA1*0301(31.63％)최고，*0401(1.0 2％)최저。잡방총체검험표명，해족군여북방륙개한인군체、만족、신가파군체급신강유오 이족무현저차이(P>0.05),단유개별기인빈솔적현저차이；포의족、태족、태만군체 조성복 잡, 여기타군체유흔대현저차이（P>0.001)；엄동한인여엄서장족여기타군체야유겁 기현저 적차이；합살극족여유오이족상사；유오이족여부분북방한족병무현저차이；장족여합살극 족、신가파군체무현저차이。결론： 남방각족군DQA1적복잡구성，가능여기원적다양성혹지 역배경유관。양비이족족군HLA-DQA1구성유북방족군특정。
Objective:To investigate HLA-DQA1 alleles distribution in the Yichu of Yangbi county, Yunnan province, compared with other Chinese group.Methods: PCR -RFLP.Results: Of 8 DQA1 alleles studied, DQA1*0301 (allele frequency 31.63%) is the most common allele in this Yichu, and DQA1*0401 (1.02%) is the rarest. Chi -s quare test shows that Yangbi Yichu has no significant difference with six northe rn Han groups, Man, Singaporean and Uygurs of Xinjiang. In contrast, Buyi, Dai a nd Taiwanese is much more complicated with a significant difference from other g roups. A similar observation was found in Guangdong Han and Guangxi Zhuang. Si mi lar to Kazak, Uygurs showed no significant difference with some of northern Han groups. Tibetans have no significant difference with Kazaks and Singaporean. Conclusion: DQA1 complexity of southern ethnic group is probably result of mutilpl e origin or stress of different environment.Yangbi Yi ethnic group has characte ristic of Northern group.