CAJ | 학술논문

对1979～1998年我国各省、自治区和直辖市报告的梅毒疫情进行流行病学分析。结果发现我国自1979午重庆市报告首例梅毒病例后，报病数逐年增多，尤其是1993年后，呈现大幅上升。至1998年全国梅毒报告发病率达4.31/10万，为1993年的25倍。1993～1998年梅毒发病率年均增长90.9％。由沿海开放城市向内陆城市再向农村地区蔓延。至1998年全国有4个梅毒高发区(珠江三角洲、长江三角洲、东北、京津地区)。不同地区梅毒发病率和增长速度相差较大。男女梅毒病例数的比例有缩小趋势，由1991年的1.72：1，缩小至1998年的1.10：1。年龄别发病率以20～岁组最高，10～14岁最低。1996年后二期梅毒病例多于一期梅毒，按性别分层分析，男女梅毒病例临床分期构成有高度显特差异(P＜0.001)，男性以一期最多，女性则以二期最多。近年梅毒在8种性病中的构成逐年增高。由1994年的1.53％上升至1998年的8.50％。提示我国梅毒流行形势日益严峻，应引起足够重视。
대1979～1998년아국각성、자치구화직할시보고적매독역정진행류행병학분석。결과발현아국자1979오중경시보고수례매독병례후，보병수축년증다，우기시1993년후，정현대폭상승。지1998년전국매독보고발병솔체4.31/10만，위1993년적25배。1993～1998년매독발병솔년균증장90.9％。유연해개방성시향내륙성시재향농촌지구만연。지1998년전국유4개매독고발구(주강삼각주、장강삼각주、동북、경진지구)。불동지구매독발병솔화증장속도상차교대。남녀매독병례수적비례유축소추세，유1991년적1.72：1，축소지1998년적1.10：1。년령별발병솔이20～세조최고，10～14세최저。1996년후이기매독병례다우일기매독，안성별분층분석，남녀매독병례림상분기구성유고도현특차이(P＜0.001)，남성이일기최다，녀성칙이이기최다。근년매독재8충성병중적구성축년증고。유1994년적1.53％상승지1998년적8.50％。제시아국매독류행형세일익엄준，응인기족구중시。
To understand trends and epidemiological characters ofsyphilis past years in China and provide scientific basis for makingcontrol strategies. From 1979 to 1998, syphilis case - reporting da-ta collected from all provinces, autonomous regions and municipal-ities were analyzed with epidemiological methods. Results Sincefirst case of syphilis was reported in Chongqing in 1979, the re-ported cases have increased year by year, especially after 1993,they raised sharply. The incidence rate of syphilis was 4.31/100,000 in the country in 1998. which was as 25 times as that in1993. In the period of 1993 - 1998, annual average growth of in-cidence rate of syphilis was 90.9 %. Syphilis spread from coastalopening cities to inland urban area, then to rural area. There were4 regions with high incidence rate of syphilis in 1998(the YangtseDelta, the Zhujiang River Deita, the Nontheast, Beijing andTianjin area), and there was a great difference in incidence andgrowth of syphilis in different areas. the ratio of male and felmalecases was reducing from 1.72:1 in 1991 to 1.10:1 in 1998. 20 -agegroup rate was the highest and 10 - 14 was the lowest. Sec-ondary syphilis cases have been more than that of primary onessince 1996. There was highly significant between in constitutes ofclinical stage of syphilis cases of male and female ( P ＜ 0. 001 ),which primary syphilis was tlle most common in male and sec-ondary ones in felmale. Recently the propotion ofsyphilis in 8 sex-ually transmitted diseases mounted gradually from 1.53 % in 1994to 8.50% in 1998. The study indicated that the Epidemiologicalsituation of Syphilis in China became severer, we should pay seri-ously attention to that.