国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
10期
1487-1489
,共3页
神经节苷脂%免疫球蛋白%中重度%缺氧缺血性脑病
神經節苷脂%免疫毬蛋白%中重度%缺氧缺血性腦病
신경절감지%면역구단백%중중도%결양결혈성뇌병
Ganglioside%Immunoglobulin%Moderately severe%Hypoxic-ischemic%Encephalopathy
目的 探讨神经节苷脂联合大剂量免疫球蛋白治疗中重度新生儿缺氧缺血性脑病的临床效果.方法 随机抽取我院收治的80例中重度缺氧缺血性脑病新生儿,随机分为两组.对照组38例,行常规治疗；实验组42例,行神经节苷脂联合大剂量免疫球蛋白治疗.随访1～2个月,比较两组患儿临床神经症状恢复时间和新生儿行为神经评分.结果 两组患儿神经症状恢复时间和治疗后NBNA评分均有显著差异(P＜0.05),且实验组疗效优于对照组.结论 应用神经节苷脂联合大剂量免疫球蛋白治疗新生儿缺血缺氧性脑病可有效缩短病程,治疗效果好.
目的 探討神經節苷脂聯閤大劑量免疫毬蛋白治療中重度新生兒缺氧缺血性腦病的臨床效果.方法 隨機抽取我院收治的80例中重度缺氧缺血性腦病新生兒,隨機分為兩組.對照組38例,行常規治療；實驗組42例,行神經節苷脂聯閤大劑量免疫毬蛋白治療.隨訪1～2箇月,比較兩組患兒臨床神經癥狀恢複時間和新生兒行為神經評分.結果 兩組患兒神經癥狀恢複時間和治療後NBNA評分均有顯著差異(P＜0.05),且實驗組療效優于對照組.結論 應用神經節苷脂聯閤大劑量免疫毬蛋白治療新生兒缺血缺氧性腦病可有效縮短病程,治療效果好.
목적 탐토신경절감지연합대제량면역구단백치료중중도신생인결양결혈성뇌병적림상효과.방법 수궤추취아원수치적80례중중도결양결혈성뇌병신생인,수궤분위량조.대조조38례,행상규치료；실험조42례,행신경절감지연합대제량면역구단백치료.수방1～2개월,비교량조환인림상신경증상회복시간화신생인행위신경평분.결과 량조환인신경증상회복시간화치료후NBNA평분균유현저차이(P＜0.05),차실험조료효우우대조조.결론 응용신경절감지연합대제량면역구단백치료신생인결혈결양성뇌병가유효축단병정,치료효과호.
Objective To investigate the clinical effect of ganglioside with high-dose immunoglobulin therapy treating on severe neonatal hypoxic-ischemic encephalopathy.Methods 80 severe hypoxic-ischemic encephalopathy neonate were selected and randomly divided into experimental group(42 cases) and control group(38 cases).Control group received conventional treatment,while experimental group received ganglioside with high-dose immunoglobulin therapy.Followed up 1 ～ 2 months,then compared recovery time and neonatal behavioral neurological assessment of two groups.Results The neurological symptoms after treatment,recovery time and NBNA scores of two groups had significant differences(P ＜ 0.05),and the curative effect of experimental group was better than that of control group.Gonclusion The application of ganglioside with high-dose immunoglobulin therapy treating on neonatal hypoxic-ischemic encephalopathy can effectively shorten the course of treatment.
