CAJ | 학술논문

目的探讨Ⅱ期结直肠术后复发转移的危险因素.方法回顾性分析2000年1月至2003年12月我院收治的192例Ⅱ期结直肠癌患者的临床资料,并分析复发转移相关因素.结果本组患者行根治术后出现复发转移68例,其中肝转移19例,肺转移15例,多脏器转移9例,骨转移5例,腹腔转移5例,脑转移3例,肾转移1例,吻合口复发11例.术前癌胚抗原(CEA)水平、肿瘤分化程度、肿瘤浸润深度、淋巴结清扫个数、有无脉管瘤栓是术后复发转移的主要影响因素(χ~2 值分别为8.566、7.602、6.505、11.892、6.995,P均<O.05).logistic 回归分析表明术前CEA水平、肿瘤分化程度及淋巴结清扫个数为Ⅱ期结直肠癌根治术后复发转移的独立危险因素.结论 Ⅱ期结直肠癌术后复发转移最常见部位为肝脏,提高淋巴结清扫个数有助于降低复发转移风险.
목적 탐토Ⅱ기결직장술후복발전이적위험인소.방법 회고성분석2000년1월지2003년12월아원수치적192례Ⅱ기결직장암환자적림상자료,병분석복발전이상관인소.결과 본조환자행근치술후출현복발전이68례,기중간전이19례,폐전이15례,다장기전이9례,골전이5례,복강전이5례,뇌전이3례,신전이1례,문합구복발11례.술전암배항원(CEA)수평、종류분화정도、종류침윤심도、림파결청소개수、유무맥관류전시술후복발전이적주요영향인소(χ~2 치분별위8.566、7.602、6.505、11.892、6.995,P균<O.05).logistic 회귀분석표명술전CEA수평、종류분화정도급림파결청소개수위Ⅱ기결직장암근치술후복발전이적독립위험인소.결론 Ⅱ기결직장암술후복발전이최상견부위위간장,제고림파결청소개수유조우강저복발전이풍험.
Objective To investigate the risk factors of metastasis and recurrence for stage Ⅱcolorectal carcinoma.Methods From January,2000 to December,2003,clinical records of 192 stage Ⅱ colorectal carcinoma patients who had underwent curative resection were retrospectively analyzed.Results 68 patients experienced relapse,including 19 hepatic metastasis,15 pulmonary metastasis,5 bone metastasis,3 brain metastasis,1 kidney meta stasis and 11 stomal recurrence.Preoperative CEA level,histological differentiation,T stage,lymph node harvest and vessel invasion were the main factors correlated with metastasis/recurrence(χ~2 values were 8.566,7.602,6.505, 11.892 and 6.995,P<O.05).Logistic regression analysis showed that preoperative CEA level,histological differentiation,and lymph node harvested were independent risk factors.Conclusions Liver is the most common metastatic site after curative resection.Improved lymph node harvest could reduce metastasis or recurrence risk.