CAJ | 학술논문

目的研究担子菌黄卷缘齿菌Hydnum repandum的化学成分.方法通过硅胶、Sephadex LH-20、反相硅胶柱色谱分离化合物,运用氢谱、碳谱、二维核磁共振(1H-1HCOSY,HMQC,HMBC,NOESY)、质谱、高分辨质谱、旋光鉴定结果.结果共分离鉴定了11个化合物,分别是:sarcodonin A(Ⅰ)、scabronine B(Ⅱ)、3β-羟基-5α,8α-过氧麦角甾-6,22-二烯-3β-醇(Ⅲ)、(22E,24R)-麦角甾-7,22-二烯-3β-,5α,6β-三醇(Ⅳ)、(22E,24R)-麦角甾-7,22-二烯-3β-醇(Ⅴ)、苯甲酸(Ⅵ)、对羟基苯甲醛(Ⅶ)、对羟基苯甲酸乙酯(Ⅷ)、乙基-β-D-吡喃葡萄糖苷(Ⅸ)、硫代乙酸酐(Ⅹ)、(2S,2'R,3S,4R)-2-(2-羟基-十八碳酰胺)二十二碳烷-1,3,4-三醇(Ⅺ).结论所有化合物都是首次在黄卷缘齿菌中分到.
목적연구담자균황권연치균Hydnum repandum적화학성분.방법통과규효、Sephadex LH-20、반상규효주색보분리화합물,운용경보、탄보、이유핵자공진(1H-1HCOSY,HMQC,HMBC,NOESY)、질보、고분변질보、선광감정결과.결과공분리감정료11개화합물,분별시:sarcodonin A(Ⅰ)、scabronine B(Ⅱ)、3β-간기-5α,8α-과양맥각치-6,22-이희-3β-순(Ⅲ)、(22E,24R)-맥각치-7,22-이희-3β-,5α,6β-삼순(Ⅳ)、(22E,24R)-맥각치-7,22-이희-3β-순(Ⅴ)、분갑산(Ⅵ)、대간기분갑철(Ⅶ)、대간기분갑산을지(Ⅷ)、을기-β-D-필남포도당감(Ⅸ)、류대을산항(Ⅹ)、(2S,2'R,3S,4R)-2-(2-간기-십팔탄선알)이십이탄완-1,3,4-삼순(Ⅺ).결론소유화합물도시수차재황권연치균중분도.
Objective To study the chemical constituents of the fruiting bodies of Hydnum repandum.Methods Separation and purification were performed on silica gel, Sephadex LH-20 and ODS CC. Their sturctures were established by 2D-NMR (1H-1HCOSY, HMQC, HMBC, and NOESY), MS, HR-MS spectra, and ORD data. Results Eleven compounds were obtained and identified as sarcodonin A ( Ⅰ ),scabronine B (Ⅱ), 3β-hydroxy-5α, 8α-epidioxyergosta-6, 22-dien (Ⅲ), (22E, 24R)-ergosta-7, 22-diene3β, 5α, 6β- triol (Ⅳ), (22E, 24R)-ergosta-7, 22-diene-3β-ol (Ⅴ), benzoic acid (Ⅵ), 4-hydroxylbenzaldehyde (Ⅶ), 4-monopropanoylbenzenediol (Ⅷ), ethyl-β-D-glucopyranoside (Ⅸ), thioacetic anhydride ( Ⅹ ), (2S, 2'R, 3S, 4R)-2-(2-hydroxyoctadecanoylamino) docosane-1, 3, 4-triol (Ⅺ). Conclusion All of the compounds are isolated from this fungus for the first time.