中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
11期
1485-1487
,共3页
尿激酶%溶栓%心肌梗死%血液流变学
尿激酶%溶栓%心肌梗死%血液流變學
뇨격매%용전%심기경사%혈액류변학
Urokinase%Thrombolysis%Myocardiai infarction%Hemorheology
目的 研究尿激酶对急性心肌梗死(AMI)的治疗作用及其对血液流变学的影响,为临床治疗提供依据.方法 将96例急性心肌梗死患者分为尿激酶治疗组和对照组,分别于治疗前后3h采血进行血液流变学检查.结果 溶栓组AMI患者再通率显著高于对照组;溶栓组CK和CKMB治疗后显著好转,与对照组差异有统计学意义;AMI患者各项血液流变学指标均明显异常,尿激酶早期静脉溶栓后各项血液流变学指标均显著改善.结论AMI患者早期采用尿激酶静脉溶栓可显著改善血液流变学各项异常指标,对缩小梗死面积、恢复心肌血供、提高再通率,减少并发症具有重要作用.
目的 研究尿激酶對急性心肌梗死(AMI)的治療作用及其對血液流變學的影響,為臨床治療提供依據.方法 將96例急性心肌梗死患者分為尿激酶治療組和對照組,分彆于治療前後3h採血進行血液流變學檢查.結果 溶栓組AMI患者再通率顯著高于對照組;溶栓組CK和CKMB治療後顯著好轉,與對照組差異有統計學意義;AMI患者各項血液流變學指標均明顯異常,尿激酶早期靜脈溶栓後各項血液流變學指標均顯著改善.結論AMI患者早期採用尿激酶靜脈溶栓可顯著改善血液流變學各項異常指標,對縮小梗死麵積、恢複心肌血供、提高再通率,減少併髮癥具有重要作用.
목적 연구뇨격매대급성심기경사(AMI)적치료작용급기대혈액류변학적영향,위림상치료제공의거.방법 장96례급성심기경사환자분위뇨격매치료조화대조조,분별우치료전후3h채혈진행혈액류변학검사.결과 용전조AMI환자재통솔현저고우대조조;용전조CK화CKMB치료후현저호전,여대조조차이유통계학의의;AMI환자각항혈액류변학지표균명현이상,뇨격매조기정맥용전후각항혈액류변학지표균현저개선.결론AMI환자조기채용뇨격매정맥용전가현저개선혈액류변학각항이상지표,대축소경사면적、회복심기혈공、제고재통솔,감소병발증구유중요작용.
Objective To study the therapeutic effects of urokinase in the treatment of acute myocardiai in-farction(AMI) and its effect on the changes of hemorheological.Methods 96 patients with AMI were divided into the group treatment with urokinase and the control group.blood samples taken from every group before treatment and three hours after therapy were derected.Results The recanalization rate was significantly higher in the group treatment with urokinase than control group.CK and CKMB significantly improved after treatment with urokinase than control.The indexes of hemorheology in the patients with AMI were abnormal,which were improved after intravenous onjection with urokinase.Conclusion Early using of urokinase in AMI could improve the indexes of hemorheology sign-ficently,and it could shrink the area of infarction,recover reperfusion rate and reduce mortality rate.
