中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2009年
8期
820-823
,共4页
蔡卫%邓佳云%欧阳兵%李平%李锋%周定友%徐家沅%沙开芬%陈晓芳
蔡衛%鄧佳雲%歐暘兵%李平%李鋒%週定友%徐傢沅%沙開芬%陳曉芳
채위%산가운%구양병%리평%리봉%주정우%서가원%사개분%진효방
克山病%监测%流行特点
剋山病%鑑測%流行特點
극산병%감측%류행특점
Keshan disease%Surveillance%Epidemical characteristic
目的 探索四川省克山病病情演变规律与流行特点.方法 采用描述流行病学方法,收集汇总1990-2008年资料数据,并进行统计分析.结果 四川省克山病19年间,急型、亚急型克山病累计发病87例.病例均为农业户儿童,彝族儿童居多,发病年龄最小5月龄,最大18岁,2～6岁最多,年发病率波动在0/10万～1.73/10万之间,以1999年最高(1.73/10万);临床慢型、潜在型克山病累计检出310例,总检出率0.28%～2.8%,以1992年最高;19年间的病区人群硒营养水平,1995年最低(0.1345μg/g),1990-2000年次之(0.1558 μg/g),属于病区硒水平.结论 四川省克山病病情演变过程可分为5个阶段,2个上升阶段,3个下降阶段,各阶段差异均有统计学意义,而病情下降的3个阶段均为采取了以补硒为主要手段的防控措施之后,表明贫硒与克山病发病关系密切.
目的 探索四川省剋山病病情縯變規律與流行特點.方法 採用描述流行病學方法,收集彙總1990-2008年資料數據,併進行統計分析.結果 四川省剋山病19年間,急型、亞急型剋山病纍計髮病87例.病例均為農業戶兒童,彝族兒童居多,髮病年齡最小5月齡,最大18歲,2～6歲最多,年髮病率波動在0/10萬～1.73/10萬之間,以1999年最高(1.73/10萬);臨床慢型、潛在型剋山病纍計檢齣310例,總檢齣率0.28%～2.8%,以1992年最高;19年間的病區人群硒營養水平,1995年最低(0.1345μg/g),1990-2000年次之(0.1558 μg/g),屬于病區硒水平.結論 四川省剋山病病情縯變過程可分為5箇階段,2箇上升階段,3箇下降階段,各階段差異均有統計學意義,而病情下降的3箇階段均為採取瞭以補硒為主要手段的防控措施之後,錶明貧硒與剋山病髮病關繫密切.
목적 탐색사천성극산병병정연변규률여류행특점.방법 채용묘술류행병학방법,수집회총1990-2008년자료수거,병진행통계분석.결과 사천성극산병19년간,급형、아급형극산병루계발병87례.병례균위농업호인동,이족인동거다,발병년령최소5월령,최대18세,2～6세최다,년발병솔파동재0/10만～1.73/10만지간,이1999년최고(1.73/10만);림상만형、잠재형극산병루계검출310례,총검출솔0.28%～2.8%,이1992년최고;19년간적병구인군서영양수평,1995년최저(0.1345μg/g),1990-2000년차지(0.1558 μg/g),속우병구서수평.결론 사천성극산병병정연변과정가분위5개계단,2개상승계단,3개하강계단,각계단차이균유통계학의의,이병정하강적3개계단균위채취료이보서위주요수단적방공조시지후,표명빈서여극산병발병관계밀절.
Objective To study the epidemiological characteristics of Keshan disease(KD) and its fiend so as to provide evidences for further research,prevention and treatment of the disease in Sichuan province.Methods Based on KD related data from 1990 to 2008,descriptive method was used to analyze the epidemiological characteristics of KD.Results 87 KD cases were identified during the 19 years.All cases were children from the countryside,with majority of them were Yi nationality.Age of the patients ranged from 5 months to 18 years,with majority at 2-6 year-olds.The annual incidence rates Were from 0/100 000 to 1.73/100 000 with 1999 the highest(1.73/100 000).A total number of 310 preclinical or chronic KD cases were identified and the total detection rates were between 0.28% and 2.8%.with 1992 the highest.As for levels of blood selenium during the 19 years:1995 appeared the lowest(0.1345 μg/g),followed by 1990-2000(0.1558 μg/g) but all of them fell in to the level in the KD epidemic areas.Conclusion There were 5 stages in the development trend of KD disease in Sichuan province,with 2 ascending and 3 descending.The differences between any of the two stages were statistically significant.The 3 descending stages all appeared right after the selenium supplement intervention was taken.Our data showed that the program of selenium supplement was closely related to the incidence of KD,suggesting that a long term mechanism of Selenium supplement in the epidemic areas should be taking into account.
