CAJ | 학술논문

NADPH氧化酶类是一个多亚基酶复合体家族,催化活性氧(reactive oxygen species,ROS)的产生.大量研究显示,氧化应激在脑缺血再灌注损伤中起着十分重要的作用.而一些关于NADPH氧化酶在脑缺血后表达改变的发现,为缺血性卒中的防治提供了新的思路.NADPH氧化酶有可能会成为一个新的治疗靶点.
NADPH양화매류시일개다아기매복합체가족,최화활성양(reactive oxygen species,ROS)적산생.대량연구현시,양화응격재뇌결혈재관주손상중기착십분중요적작용.이일사관우NADPH양화매재뇌결혈후표체개변적발현,위결혈성졸중적방치제공료신적사로.NADPH양화매유가능회성위일개신적치료파점.
NADPH oxidases are a family of multi-subunit enzyme eomplexes.It catalyzes the production of reactive oxygen species (ROS).A large number of studies have shown that oxidative stress plays a very important role in cerebral ischemia-reperfusion injury,and the find of the expression changes about NADPH oxidase after cerebral ischemia may provide a new idea for the prevention and treatment of ischemic stroke.NADPH oxidase may become a new therapeutic target.