CAJ | 학술논문

目的探讨实时剪切波弹性成像在甲状腺实性结节良恶性鉴别诊断中的应用价值.方法应用实时剪切波弹性成像技术对83例患者共113个甲状腺实性结节测量杨氏模量值,与手术病理结果进行对照,绘制ROC曲线图,获得区分甲状腺结节良恶性的杨氏模量临界值.结果 ①良性组杨氏模量值为(23.57±9.35)kPa,恶性组为(43.73±19.82)kPa,两者差异有统计学意义(t =6.31,P=0.00).②通过ROC曲线确定良、恶性结节杨氏模量值的临界点为27.49 kPa,其敏感性为93.2％,特异性为81.2％,准确性为85.8％,ROC曲线下面积为0.91.结论实时剪切波弹性成像技术可对甲状腺结节良恶性作出定量诊断,为鉴别甲状腺结节的良恶性提供了一种新的方法.
목적 탐토실시전절파탄성성상재갑상선실성결절량악성감별진단중적응용개치.방법 응용실시전절파탄성성상기술대83례환자공113개갑상선실성결절측량양씨모량치,여수술병리결과진행대조,회제ROC곡선도,획득구분갑상선결절량악성적양씨모량림계치.결과 ①량성조양씨모량치위(23.57±9.35)kPa,악성조위(43.73±19.82)kPa,량자차이유통계학의의(t =6.31,P=0.00).②통과ROC곡선학정량、악성결절양씨모량치적림계점위27.49 kPa,기민감성위93.2％,특이성위81.2％,준학성위85.8％,ROC곡선하면적위0.91.결론 실시전절파탄성성상기술가대갑상선결절량악성작출정량진단,위감별갑상선결절적량악성제공료일충신적방법.
Objective To evaluate the clinical value of Young's modulus by supersonic shear wave elastography (SWE) in differential diagnosis of thyroid solid nod1ules.Methods Eighty-three patients with 113 solid nodules were examined by SWE.All the nodules were confirmed by pathology.According to Young's modulus,a receiver operating characteristic (ROC) curve was drawn,and it used to identify the value of optimal operating point for differential diagnosis of thyroid nodules.Results ① The mean of Young's modulus of benign nodules was (23.57 ± 9.35)kPa,which was significantly different from the valve of malignant nodules (43.73 ± 19.82) kPa ( t =6.31,P =0.00).(②) It showed that the optimal operating point of ROC curve as 27.49,with high sensitivity(93.2％),specificity(81.2％) and accuracy (85.8％).The area under ROC curve was 0.91.Conclusions SWE is a newly quantitative technique of ultrasonography,which is helpful to identify and distinguish in the differential diagnosis of thyroid nodules.