CAJ | 학술논문

回顾性分析2006年1月至2009年7月在本院116例经长期深静脉置管血液透析患者的临床资料,探讨导管相关感染的危险因素.其中感染组18例,非感染组98例,对置管留置时间、原发病、血常规、生化等指标比较,相关危险因素分析采用COX比例风险回归模型分析.结果显示,导管感染总体发生率在0.314次/1000个导管日.糖尿病(OR=4.011,P=0.0213)、血红蛋白＜80g/L(OR=7.181,P=0.0020)是导管相关感染的危险因素.改善患者的营养状况及纠正贫血可降低导管相关感染.
회고성분석2006년1월지2009년7월재본원116례경장기심정맥치관혈액투석환자적림상자료,탐토도관상관감염적위험인소.기중감염조18례,비감염조98례,대치관류치시간、원발병、혈상규、생화등지표비교,상관위험인소분석채용COX비례풍험회귀모형분석.결과현시,도관감염총체발생솔재0.314차/1000개도관일.당뇨병(OR=4.011,P=0.0213)、혈홍단백＜80g/L(OR=7.181,P=0.0020)시도관상관감염적위험인소.개선환자적영양상황급규정빈혈가강저도관상관감염.
Clinical data of 116 patients with implanted permanent dual catheters for hemodialysis,including 18 with infection and 98 non-infection, during January 2006 and July 2009 were retrospectively analyzed to study risk factors for catheter-related bacteremia (CRB). Duration of catheter implantation,primary disease, routine blood examinations and blood biochemical examination of the patients were analyzed between the two groups. COX proportional hazard regression analysis was performed for all predictor variables. Results showed that overall incidence of bacteremic episodes was 0. 314 per 1000 catheter-day.Compared to that in infection group, levels of hemoglobin, plasma albumin, peripheral lymphocyte count and ratio of CD4/CD8 in non-infection group were significantly higher ( all P ＜ 0. 05 ), and OR of CRB were 4. 011 (P =0. 0213) for diabetes mellitus and 7. 181 for hemoglobin level less than 80g/L (P = 0. 0020),respectively. It is suggested that improving nutrition status and correcting anemia for patients with hemodialysis are necessary to reduce CRB.