CAJ | 학술논문

目的通过绘制时间信号强度曲线,探讨MRI快速序列动态增强在前列腺癌诊断及鉴别诊断中的价值.方法对5例无泌尿系症状健康对照者、13例经病理证实的前列腺癌及36例前列腺增生行MR平扫、动态增强及延迟扫描,测量并计算病灶和正常组织的相对信号强度值,并绘制正常周围带、前列腺癌与增生三者的时间信号强度曲线.结果正常周围带轻度强化,并缓慢上升至晚期达峰值;36例前列腺增生早期明显强化并逐渐上升至中晚期达峰值后缓慢下降;13例前列腺癌中9例早期明显强化,并快速下降,4例T2WI像上弥漫性病灶呈现中晚期强化.结论正常周围带、前列腺癌及前列腺增生的动态强化方式明显不同,应用动态增强扫描可对前列腺癌的诊断与鉴别诊断起积极作用.
목적통과회제시간신호강도곡선,탐토MRI쾌속서렬동태증강재전렬선암진단급감별진단중적개치.방법대5례무비뇨계증상건강대조자、13례경병리증실적전렬선암급36례전렬선증생행MR평소、동태증강급연지소묘,측량병계산병조화정상조직적상대신호강도치,병회제정상주위대、전렬선암여증생삼자적시간신호강도곡선.결과정상주위대경도강화,병완만상승지만기체봉치;36례전렬선증생조기명현강화병축점상승지중만기체봉치후완만하강;13례전렬선암중9례조기명현강화,병쾌속하강,4례T2WI상상미만성병조정현중만기강화.결론정상주위대、전렬선암급전렬선증생적동태강화방식명현불동,응용동태증강소묘가대전렬선암적진단여감별진단기적겁작용.
Objective: To assess the role of dynamic contrast-enhanced MRI (DCE-MRI) in the diagnosis and differentiation of prostatic cancer (PC). Methods: Five volunteers, 36 patients with benign prostatic hyperplasia (BPH) and 13 patients with biopsy-proven prostate cancer underwent conventional MRI, DCEMRI and delayed enhancement MRI. The value of the signal intensity in DCE-MRI was measured and calculated to draw the time-signal intensity curve of the normal peripheral zone (PZ), the prostate cancer and the benign prostatic hyperplasia. Results: In DCE-MRI, the normal peripheral zone was enhanced mildly and slowly and the peak value was located in late phase. The enhancement of the lesions in 36patients with the benign prostatic hyperplasia was obvious in early phase and strengthened gradually, and then turned to decrease in late phase after peak value. The lesions in 9 of 13 cases with prostate cancer were enhanced obviously in early phase and washed out rapidly, and the peak value was located in early phase, but the peak value was in mediate and late phase in the other 4 cases with diffuse lesion in the prostate on T2WI. Conclusion: In DCE-MRI, the enhancement patterns of the normal peripheral zone,the prostate cancer and the benign prostatic hyperplasia were significantly different. DCE-MRI was very useful in the diagnosis and differentiation of prostate cancer.