CAJ | 학술논문

提出了一种简便易行的对磁性纳米粒子表面进行氨基化的方法.首先使用化学共沉淀法合成了粒径为10 nm左右的Fe_3O_4纳米粒子,然后用阿仑膦酸钠对其表面进行修饰,使其表面具有了功能化的氨基.利用透射电子显微镜(TEM)、X射线衍射(XRD)、振动样品磁强计(VSM)、动态光散射(DLS)仪、热重分析(TGA)仪、傅里叶变换红外(FT-IR)光谱仪、X射线光电子能谱(XPS)仪等对其进行表征.结果显示磁性纳米粒子表面被成功地修饰了一层双膦酸分子.所制备的纳米粒子可在pH=6.3稳定存在4周以上.
제출료일충간편역행적대자성납미입자표면진행안기화적방법.수선사용화학공침정법합성료립경위10 nm좌우적Fe_3O_4납미입자,연후용아륜련산납대기표면진행수식,사기표면구유료공능화적안기.이용투사전자현미경(TEM)、X사선연사(XRD)、진동양품자강계(VSM)、동태광산사(DLS)의、열중분석(TGA)의、부리협변환홍외(FT-IR)광보의、X사선광전자능보(XPS)의등대기진행표정.결과현시자성납미입자표면피성공지수식료일층쌍련산분자.소제비적납미입자가재pH=6.3은정존재4주이상.
We propose a convenient method to synthesize surface amino-coated magnetic nanoparticles. Fe_3O_4 nanoparticles with a grain diameter of about 10 run were synthesized by the chemical co-precipitation of ferrous chloride and ferric chloride. The obtained superparamagnetic nanoparticles were surface-modified with alendronate to introduce an amino group onto their surfaces. The particles were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), vibrating sample magnetometry (VSM), dynamic light scattering (DLS), thermogra-vimetric analysis (TGA), Fourier transform infrared (FT-IR) spectroscopy, and X-ray photoelectron spectroscopy (XPS). The data showed that alendronate was successfully linked to the SPM nanoparticles. These particles are stable for more than 4 weeks without precipitation at pH= 6.3.