中华精神科杂志
中華精神科雜誌
중화정신과잡지
CHINESE JOURNA OF PSYCHIATRY
2009年
1期
29-33
,共5页
邹义壮%崔界峰%王健%陈楠%谭淑平%张东%徐泽%宋少刚%王云辉%李玥%高文静%段京辉
鄒義壯%崔界峰%王健%陳楠%譚淑平%張東%徐澤%宋少剛%王雲輝%李玥%高文靜%段京輝
추의장%최계봉%왕건%진남%담숙평%장동%서택%송소강%왕운휘%리모%고문정%단경휘
精神分裂症%认知%神经心理学测验%精神分裂症认知功能成套测验%信度%效度
精神分裂癥%認知%神經心理學測驗%精神分裂癥認知功能成套測驗%信度%效度
정신분렬증%인지%신경심이학측험%정신분렬증인지공능성투측험%신도%효도
Schizophrenia%Cognition%Neuropsychological tests%MCCB%Reliability%Validity
目的 对中文版精神分裂症认知功能成套测验(MCCB)的信度及效度进行临床测试.方法 对122例符合美国精神障碍诊断与统计手册第4版精神分裂症诊断标准的住院患者(患者组)进行MCCB测验,4周后重测,同期接受威斯康星卡片分类测验(WCST)、瑞文推理测验(RAVEN)、色词测验(Stroop)及阳性和阴性症状量表(PANSS)测查;并与122名性别、年龄和文化程度与患者组相匹配的社区正常人(对照组)进行比较.结果 (1)MCCB重测相关系数为0.88,P<0.001;(2)评定者间组内相关系数为0.97,P<0.001;(3)MCCB的A、B版本间的复本相关系数为0.64～0.74,P<0.001;A、B版本间的差异无统计学意义(P>0.05);(4)患者组各个分测验得分均低于对照组(P<0.001);逻辑回归分析,用MCCB区分精神分裂症患者与正常人,符合率达到84.8%(P<0.001),敏感性83.6%,特异性86.1%;(5)关联效度:MCCB与WCST、RAVEN和Stroop呈显著性相关(r=0.54～0.55),P<0.001;(6)结构效度:验证性因素分析证明中文版MCCB与英文版7个维度结构模型拟合良好;(7)MCCB平均完成时间为(58±10)min,耐受性和操作性达到中等偏上水平.结论 中文版MCCB的重测信度、评定者间信度、同质性信度、复本信度、关联效度、结构效度和效标效度等指标满足心理测量学要求,MCCB作为精神分裂症患者认知功能疗效评估的新标准,值得进一步修订和完善.
目的 對中文版精神分裂癥認知功能成套測驗(MCCB)的信度及效度進行臨床測試.方法 對122例符閤美國精神障礙診斷與統計手冊第4版精神分裂癥診斷標準的住院患者(患者組)進行MCCB測驗,4週後重測,同期接受威斯康星卡片分類測驗(WCST)、瑞文推理測驗(RAVEN)、色詞測驗(Stroop)及暘性和陰性癥狀量錶(PANSS)測查;併與122名性彆、年齡和文化程度與患者組相匹配的社區正常人(對照組)進行比較.結果 (1)MCCB重測相關繫數為0.88,P<0.001;(2)評定者間組內相關繫數為0.97,P<0.001;(3)MCCB的A、B版本間的複本相關繫數為0.64～0.74,P<0.001;A、B版本間的差異無統計學意義(P>0.05);(4)患者組各箇分測驗得分均低于對照組(P<0.001);邏輯迴歸分析,用MCCB區分精神分裂癥患者與正常人,符閤率達到84.8%(P<0.001),敏感性83.6%,特異性86.1%;(5)關聯效度:MCCB與WCST、RAVEN和Stroop呈顯著性相關(r=0.54～0.55),P<0.001;(6)結構效度:驗證性因素分析證明中文版MCCB與英文版7箇維度結構模型擬閤良好;(7)MCCB平均完成時間為(58±10)min,耐受性和操作性達到中等偏上水平.結論 中文版MCCB的重測信度、評定者間信度、同質性信度、複本信度、關聯效度、結構效度和效標效度等指標滿足心理測量學要求,MCCB作為精神分裂癥患者認知功能療效評估的新標準,值得進一步脩訂和完善.
목적 대중문판정신분렬증인지공능성투측험(MCCB)적신도급효도진행림상측시.방법 대122례부합미국정신장애진단여통계수책제4판정신분렬증진단표준적주원환자(환자조)진행MCCB측험,4주후중측,동기접수위사강성잡편분류측험(WCST)、서문추리측험(RAVEN)、색사측험(Stroop)급양성화음성증상량표(PANSS)측사;병여122명성별、년령화문화정도여환자조상필배적사구정상인(대조조)진행비교.결과 (1)MCCB중측상관계수위0.88,P<0.001;(2)평정자간조내상관계수위0.97,P<0.001;(3)MCCB적A、B판본간적복본상관계수위0.64～0.74,P<0.001;A、B판본간적차이무통계학의의(P>0.05);(4)환자조각개분측험득분균저우대조조(P<0.001);라집회귀분석,용MCCB구분정신분렬증환자여정상인,부합솔체도84.8%(P<0.001),민감성83.6%,특이성86.1%;(5)관련효도:MCCB여WCST、RAVEN화Stroop정현저성상관(r=0.54～0.55),P<0.001;(6)결구효도:험증성인소분석증명중문판MCCB여영문판7개유도결구모형의합량호;(7)MCCB평균완성시간위(58±10)min,내수성화조작성체도중등편상수평.결론 중문판MCCB적중측신도、평정자간신도、동질성신도、복본신도、관련효도、결구효도화효표효도등지표만족심리측량학요구,MCCB작위정신분렬증환자인지공능료효평고적신표준,치득진일보수정화완선.
Objective To evaluate the reliability and validity of the Chinese version of Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB). Methods One hundred and twenty-two inpatients with schizophrenia according to the DSM-IV criteria were measured with the MCCB, and re-measured after 4 weeks. The patients were simultaneously measured with the WCST, RAVEN, Stroop and PANSS to test validity. The controls, including 122 normal community people matched to the patient in gender, age and education, were measured with the MCCB only. Results The test-retest reliability of MCCB composite score was 0.88 (P<0.001), and inter-raters reliability ICC of 0.97 (P<0.001). Correlation between A/B alternate forms of MCCB was 0.64-0.74 (P<0.001), with no significant difference between A/B forms (P>0.05). In comparison with normal control, the MCCB scores in schizophrenia were significant lower (P<0.001). Using MCCB scores to classify schizophrenia and normal people by Logistic regression, the correct rate was 84.8%, with sensitivity of 83.6%, and specificity of 86.1%. All the subtests and composite scores of MCCB significantly correlated with the WCST, RAVEN and Strcop scores (P<0.05), which indicated better concurrent validity of MCCB. As to the construct validity, confirmatory factor analysis indicated that seven domains theory model of MCCB was well fired in Chinese version. The tolerability and practicabihty of MCCB were acceptable, and the average performance time was (58±10) minutes. Conclusion The test-retest, inter-raters, consistent and A/B alternate form reliability, concurrent, structure and diagnostic validity of the Chinese version of MCCB meet the requirements of psychometrics, and could be a promising tool for assessing cognitive deficit of schizophrenia patients in China.
