CAJ | 학술논문

目的观测血管瘤主干血管三维结构的形态学特征.方法收集本院2011年3～6月完整切除人体表血管瘤标本10例,石蜡包埋固定,其中经病理分期分型为消退早期且进行完整血管瘤组织连续切片1例,进行HE染色,利用计算机辅助的图片处理和三维重建技术进行主干血管结构走行的三维重建.结果成功构建了血管瘤瘤体部分主干血管的三维结构形态.血管瘤常见主供微血管3～5条,数量较少且稳定,形态结构多样,分布全面,分级尚正常.基本遵从由大到小的分级规律但走行怪异,相互之间有交通.结论血管瘤主干血管三维结构数字化血管模型可以成功构建,其特征为血管数量稳定,形态多样,对于儿童血管瘤诊治提供了新的思路.
목적 관측혈관류주간혈관삼유결구적형태학특정.방법 수집본원2011년3～6월완정절제인체표혈관류표본10례,석사포매고정,기중경병리분기분형위소퇴조기차진행완정혈관류조직련속절편1례,진행HE염색,이용계산궤보조적도편처리화삼유중건기술진행주간혈관결구주행적삼유중건.결과 성공구건료혈관류류체부분주간혈관적삼유결구형태.혈관류상견주공미혈관3～5조,수량교소차은정,형태결구다양,분포전면,분급상정상.기본준종유대도소적분급규률단주행괴이,상호지간유교통.결론 혈관류주간혈관삼유결구수자화혈관모형가이성공구건,기특정위혈관수량은정,형태다양,대우인동혈관류진치제공료신적사로.
Objective To observe morphological features of main vessel in human hemangioma via computer-assisted three-Dimensional (3-D) reconstruction. Methods 10 cases of hemangioma specimens were harvested and paraffin-embedded fixation was performed. Among them, continuous tissue biopsy was made in 1 early regression hemangioma. HE staining was conducted for all samples. The serial images were taken and processed with computer assisted 3D reconstruction. Results Partial 3 D structures of main vessel morphology in hemangioma were successfully reconstructed. The distribution and branching of main vessels could be clearly seen, which were different from normal blood vessels in human skin. The main vessel in hemangioma had 3～5 main blood vessels and presented variety and heterogeneity, as well as abundance. Their descending grade comply with rules of plenty of anastomosis and well-proportioned. Conclusions Digital vascular model of three-dimensional structure for main vessel in hemangioma can be successfully established, which is characterized by stable number of blood vessels and varied shapes. It provides a new way for the diagnosis and treatment of hemangioma in children.