CAJ | 학술논문

建立了紫外分光光度法测定药物来曲唑含量的方法.在乙腈溶液中, 来曲唑的最大吸收波长在240 nm处,摩尔吸收系数为3.396×104 L·mol~(-1)·cm~(-1),来曲唑的浓度在2.89×10~(-6)～2.31×10~(-5) mol/L范围内吸光度与浓度呈良好的线性关系.该方法操作简单,重现性好,准确,用于来曲唑片剂含量的测定,结果满意.
건립료자외분광광도법측정약물래곡서함량적방법.재을정용액중, 래곡서적최대흡수파장재240 nm처,마이흡수계수위3.396×104 L·mol~(-1)·cm~(-1),래곡서적농도재2.89×10~(-6)～2.31×10~(-5) mol/L범위내흡광도여농도정량호적선성관계.해방법조작간단,중현성호,준학,용우래곡서편제함량적측정,결과만의.
A new method for the determination of letrozole by UV spectrophotometry was developed. Using acetonitrile as solvent and 240 nm measuring wavelength, the absorbance is proportional to the concentration of letrozole in the range of 2.888×10~(-6)～2.310×10~(-5) mol/L. The method was quite simple, reproducible, accurate and reliable. It is applicable to the determination of the content of letrozole in tablet.