中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2009年
6期
451-453
,共3页
池元伟%高玉红%彭静婷%赵毅
池元偉%高玉紅%彭靜婷%趙毅
지원위%고옥홍%팽정정%조의
电生理学/利用%诊断显像/利用%神经系统疾病/诊断
電生理學/利用%診斷顯像/利用%神經繫統疾病/診斷
전생이학/이용%진단현상/이용%신경계통질병/진단
Electrophysiology/utilization%Magnetic resonance imaging/utilization%Nervous system diseases/diagnosis
目的 探讨Adie瞳孔的神经发病机制.方法 回顾分析具有光-近反射分离及虹膜括约肌的节段性麻痹的Adie瞳孔特征的42例患者的神经影像学和神经电生理检查资料.其中,单侧瞳孔扩大者37例,双侧瞳孔扩大者5例.患者中,23例行头颅核磁共振成像(MRI)检查,其中1例同时行头颅CT检查.另有14、5、9、18、11、5例患者分别进行神经传导速度、四肢肌电图、双下肢肌电图、视觉诱发电位(VEP)、体感诱发电位、脑电图检查.结果 23例行MRI和CT检查的患者中,13例出现中枢神经系统中线结构解剖变异或微小病变.14例同时行肌电图和神经传导速度检查的患者中,6例表现为感觉神经传导速度减慢和多发性感觉运动性周围神经损害;18例行视觉诱发电位检查的患者中,5例P100潜伏期延长;11例行体感诱发电位检查的患者中,2例显示周围神经损害;5例检查脑电网的患者中,1例显示异常.结论 周围神经损害可能是Adie瞳孔的重要发病机制,中枢神经系统损害也参与其发病.
目的 探討Adie瞳孔的神經髮病機製.方法 迴顧分析具有光-近反射分離及虹膜括約肌的節段性痳痺的Adie瞳孔特徵的42例患者的神經影像學和神經電生理檢查資料.其中,單側瞳孔擴大者37例,雙側瞳孔擴大者5例.患者中,23例行頭顱覈磁共振成像(MRI)檢查,其中1例同時行頭顱CT檢查.另有14、5、9、18、11、5例患者分彆進行神經傳導速度、四肢肌電圖、雙下肢肌電圖、視覺誘髮電位(VEP)、體感誘髮電位、腦電圖檢查.結果 23例行MRI和CT檢查的患者中,13例齣現中樞神經繫統中線結構解剖變異或微小病變.14例同時行肌電圖和神經傳導速度檢查的患者中,6例錶現為感覺神經傳導速度減慢和多髮性感覺運動性週圍神經損害;18例行視覺誘髮電位檢查的患者中,5例P100潛伏期延長;11例行體感誘髮電位檢查的患者中,2例顯示週圍神經損害;5例檢查腦電網的患者中,1例顯示異常.結論 週圍神經損害可能是Adie瞳孔的重要髮病機製,中樞神經繫統損害也參與其髮病.
목적 탐토Adie동공적신경발병궤제.방법 회고분석구유광-근반사분리급홍막괄약기적절단성마비적Adie동공특정적42례환자적신경영상학화신경전생리검사자료.기중,단측동공확대자37례,쌍측동공확대자5례.환자중,23례행두로핵자공진성상(MRI)검사,기중1례동시행두로CT검사.령유14、5、9、18、11、5례환자분별진행신경전도속도、사지기전도、쌍하지기전도、시각유발전위(VEP)、체감유발전위、뇌전도검사.결과 23례행MRI화CT검사적환자중,13례출현중추신경계통중선결구해부변이혹미소병변.14례동시행기전도화신경전도속도검사적환자중,6례표현위감각신경전도속도감만화다발성감각운동성주위신경손해;18례행시각유발전위검사적환자중,5례P100잠복기연장;11례행체감유발전위검사적환자중,2례현시주위신경손해;5례검사뇌전망적환자중,1례현시이상.결론 주위신경손해가능시Adie동공적중요발병궤제,중추신경계통손해야삼여기발병.
Objective To investigate the neuropathogenesis of Adie's pupil.Methods The neuroelectrophysiological and neuroimaging data of 42 patients with Adie's pupil (light-near dissociation and segmental palsy of iris sphincter) were retrospectively analyzed.There were 37 patients with unilateral pupil dilation and 5 patients with bilateral pupil dilation.Cranial magnetic resonance imaging (MRI,23 patients),Cranial CT scanning (1 patient),nerve conduction velocity (NCV,14 patients),limb electromyogram (EMG,5 patients),both lower extremities EMG (9 patients),visual evoked potential (VEP,18 patients),somatosensory evoked potential (SEP,11 patients) and electroencephalograms (EEG,5 patients) were performed on some of those patients.Results Central nervous system midline anatomic variations or minor lesions were found in 13/23 cases of MRI/CT imaging.Slowed sensory NCV and multiple sensory-motor peripheral nerve damages were evident in 6/14 cases of the NCV/EMG assay.5/18 patients showed prolonged latency of VEP P100.2/11 cases showed peripheral nerve damage in SEP recording.and 1/5 cases showed abnormal EEG.Conclusion Peripheral nerve damage may be an important pathogenesis of Adie's pupil,while the central nervous system damage is also involved in its pathogenesis.
