重庆医科大学学报
重慶醫科大學學報
중경의과대학학보
UNIVERSITATIS SCIENTIAE MEDICINAE CHONGQING
2010年
1期
127-130
,共4页
泌尿生殖道%泌尿生殖道感染%支原体感染%药敏分析
泌尿生殖道%泌尿生殖道感染%支原體感染%藥敏分析
비뇨생식도%비뇨생식도감염%지원체감염%약민분석
Gnitourinarytract%Gnitourinary tract infection%Mcoplasma infection%Drug sesceptibility
目的:了解本市解脲支原体(Uu)和人型支原体(Mh)引起的泌尿生殖道感染及其药物敏感情况.方法:采用支原体培养、鉴定、药敏一体化试剂盒,对8494例疑为支原体感染患者的泌尿生殖道分泌物进行培养,并测定其对10种常用抗生素的敏感性.结果:8494例可疑病例中支原体培养阳性2 735例(32.2%),其中单纯解脲支原体(Uu)感染2239例(26.4%),单纯人型支原体(Mh)感染29例(0.3%),Uu与Mh双重感染467例(5.5%).药敏试验结果显示,Uu对美满霉素、强力霉素、克拉霉素、阿奇霉素、交沙霉素、罗红霉素敏感.敏感率分别为96.4%、95.4%、94.4%、87.1%、74.2%、73.3%,对大观霉素敏感率仅为6.5%;Mh对强力霉素、美满霉素、交沙霉素、林可霉素有较高的敏感率,敏感率分别为100%、96.6%、96.6%、86.2%,对罗红霉素、阿齐霉素、克拉霉素敏感率仅分别为O%、0%,3.4%;Uu+Mh对美满霉素、强力霉素最敏感,其次为交沙霉素,敏感率分别为92.1%、89.7%和61.2%,对罗红霉素、阿齐霉素、克拉霉素、大观霉索敏感率仅分别为3.9%、5.2%、8.6%、9.4%.结论:支原体感染是引起泌尿生殖系非淋菌炎症的主要病原体之一,其感染以Uu感染为主;对支原体感染的治疗,要根据药物敏试验结果合理选用抗生素,降低耐药菌株的产生.
目的:瞭解本市解脲支原體(Uu)和人型支原體(Mh)引起的泌尿生殖道感染及其藥物敏感情況.方法:採用支原體培養、鑒定、藥敏一體化試劑盒,對8494例疑為支原體感染患者的泌尿生殖道分泌物進行培養,併測定其對10種常用抗生素的敏感性.結果:8494例可疑病例中支原體培養暘性2 735例(32.2%),其中單純解脲支原體(Uu)感染2239例(26.4%),單純人型支原體(Mh)感染29例(0.3%),Uu與Mh雙重感染467例(5.5%).藥敏試驗結果顯示,Uu對美滿黴素、彊力黴素、剋拉黴素、阿奇黴素、交沙黴素、囉紅黴素敏感.敏感率分彆為96.4%、95.4%、94.4%、87.1%、74.2%、73.3%,對大觀黴素敏感率僅為6.5%;Mh對彊力黴素、美滿黴素、交沙黴素、林可黴素有較高的敏感率,敏感率分彆為100%、96.6%、96.6%、86.2%,對囉紅黴素、阿齊黴素、剋拉黴素敏感率僅分彆為O%、0%,3.4%;Uu+Mh對美滿黴素、彊力黴素最敏感,其次為交沙黴素,敏感率分彆為92.1%、89.7%和61.2%,對囉紅黴素、阿齊黴素、剋拉黴素、大觀黴索敏感率僅分彆為3.9%、5.2%、8.6%、9.4%.結論:支原體感染是引起泌尿生殖繫非淋菌炎癥的主要病原體之一,其感染以Uu感染為主;對支原體感染的治療,要根據藥物敏試驗結果閤理選用抗生素,降低耐藥菌株的產生.
목적:료해본시해뇨지원체(Uu)화인형지원체(Mh)인기적비뇨생식도감염급기약물민감정황.방법:채용지원체배양、감정、약민일체화시제합,대8494례의위지원체감염환자적비뇨생식도분비물진행배양,병측정기대10충상용항생소적민감성.결과:8494례가의병례중지원체배양양성2 735례(32.2%),기중단순해뇨지원체(Uu)감염2239례(26.4%),단순인형지원체(Mh)감염29례(0.3%),Uu여Mh쌍중감염467례(5.5%).약민시험결과현시,Uu대미만매소、강력매소、극랍매소、아기매소、교사매소、라홍매소민감.민감솔분별위96.4%、95.4%、94.4%、87.1%、74.2%、73.3%,대대관매소민감솔부위6.5%;Mh대강력매소、미만매소、교사매소、림가매소유교고적민감솔,민감솔분별위100%、96.6%、96.6%、86.2%,대라홍매소、아제매소、극랍매소민감솔부분별위O%、0%,3.4%;Uu+Mh대미만매소、강력매소최민감,기차위교사매소,민감솔분별위92.1%、89.7%화61.2%,대라홍매소、아제매소、극랍매소、대관매색민감솔부분별위3.9%、5.2%、8.6%、9.4%.결론:지원체감염시인기비뇨생식계비림균염증적주요병원체지일,기감염이Uu감염위주;대지원체감염적치료,요근거약물민시험결과합리선용항생소,강저내약균주적산생.
Objective: to investigate the status of patients with genitourinary tract infection caused by Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh),and its drag susceptibility and resistance in Chongqing.Methods:The genitourinary tract samples from 8 494 doubtful patients with mycoplasma infection were cultured and the susceptibility of the disease to 10 routine antibiotics was measured by mycoplasma cultivation,identification and drug susceptibility integration kit Results:In the results of mycoplasma cultivation of 8 494 doubtful cases,2 735 cases were positive(32.2%),and 2239 of them were simple Uu infection(26.4%),and 29 cases were simple Mh infection(0.3%)and 467 cases were double infection(5.5%).The results of susceptibility test showed that the sensitivity of Uu to Minocycline,Deoxycycline,Clarithromycin,Azithromycin,Josamycin and Roxithromycin was 96.4%,95.4%,94.4%,87.1%,74.2%,and 73.3%,respectively, but to spectinomycin was 65%.Otherwise,the sensitivity of Mh to Deoxycycline,Minocycline,Josamycin and Lincomycin was 100%,96.6%, 96.6%,86.2%respectively,but to Roxithromycin,Azithromyein,Clarithromycin was 0%,0%,3..4% respectively.The double infection was the most sensitive to Minocycline and Deoxycycline,then to Josamycin,and the sensitivity was 92.1%,89.7%and 61.2%,respectively,but the sensitivity of it to Roxithromycin,Azithromycin,Clarithromycin,and Spectinomycin was 3.9%,52%,g6%,and 9.4% respectively.Conclusion: Mycoplasma is one of the main pathogen in genitourinary tract non-gonococcus inflammation,especially Uu infection.The therapy of mycoplasma infection should depress the production of drug resistant strain by the reasonable adoption of antibiotics according to the results of susceptibility test.
