CAJ | 학술논문

对κ-卡拉胶进行酸降解得到三种卡拉胶低聚糖,并进一步琥珀酰基化得到分子量分别为2720、4000和5960的κ-卡拉胶琥珀酰衍生物(A、B和C).对产物进行FT-IR表征,并测得其琥珀酰基取代度(DS)分别为0.61、0.29和0.83.检测了三种κ-卡拉胶琥珀酰衍生物对超氧阴离子自由基O_2~(--)、DPPH自由基、羟基自由基·OH以及过氧化氢的清除活性.结果表明:随着取代度的增加,其清除超氧阴离子自由基O_2~(--)和DPPH自由基的能力增强:随着分子量的增加,其清除羟基自由基·OH和过氧化氢的能力增强.这可能与衍生物的羟基含量、取代基团的性质以及取代度等因索有关.
대κ-잡랍효진행산강해득도삼충잡랍효저취당,병진일보호박선기화득도분자량분별위2720、4000화5960적κ-잡랍효호박선연생물(A、B화C).대산물진행FT-IR표정,병측득기호박선기취대도(DS)분별위0.61、0.29화0.83.검측료삼충κ-잡랍효호박선연생물대초양음리자자유기O_2~(--)、DPPH자유기、간기자유기·OH이급과양화경적청제활성.결과표명:수착취대도적증가,기청제초양음리자자유기O_2~(--)화DPPH자유기적능력증강:수착분자량적증가,기청제간기자유기·OH화과양화경적능력증강.저가능여연생물적간기함량、취대기단적성질이급취대도등인색유관.
Three K-Carrageenan oligossccharides were prepared by acidic degradation of κ-carrageenan.Their succilnyl derivatives with different molecular weight (A: 2720; B: 4000 ; C:5960) were synthesized with suecine anhydride.The products were characterized by FI-IR.The degrees of acylation (DS) were 0.61,0.29 and 0.83, respectively.Their an-tioxidant activities were evaluated by the scavenging of superoxide anion, 1,1-diphenyl-2-pierylhrazyl radicals (DPPH) and hydroxyl radical and hydrogen peroxide.The results indicated that the scavenging effect on superoxide anion and DP-PH increased with the increasing of substituting degree;the scavenging effect on hydroxyl radical and hydrogen peroxide increased with the increasing of molecular weight.It may be related to the content of hydroxyl groups, the nature of sub-stituting group and the substituting degrees.