中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
9期
789-793
,共5页
张永红%孔伟%王海峰%樊亚超%邢成名
張永紅%孔偉%王海峰%樊亞超%邢成名
장영홍%공위%왕해봉%번아초%형성명
认知障碍%危险因素
認知障礙%危險因素
인지장애%위험인소
Cognition disorders%Risk factors
目的 探讨遗忘型、非遗忘型轻度认知功能障碍(MCI)患者危险因素的差异. 方法 收集2011年1月至2011年9月于青岛市市属3家三级医院神经内科住院的65～75岁轻度认知功能障碍患者的健康资料,应用简易智能状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)全面评价患者的认知功能,采用Petersen标准将轻度认知功能障碍的患者分成遗忘型(aMCI)89例和非遗忘型(non-aMCI) 51例两组,比较两组患者的不同危险因素. 结果 aMCI和non-aMCI组患者的糖尿病(P=0.009)比例、高胆固醇(P=0.011)比例、MoCA评分(P=0.040)差异有统计学意义.aMCI组患者MoCA评分(OR=1.081,95％CI:1.001～1.204,P=0.040)明显低于non-aMCI组；non-aMCI组糖尿病比例(OR=0.258,95％CI:0.096～0.695,P=0.009)明显高于aMCI组；aMCI组高胆固醇比例(OR=13.345,95％CI:1.127～158.085,P=0.011)明显高于non-aMCI组,且高胆固醇为aMCI的独立危险因素. 结论 不同的危险因素对aMCI、non-aMCI患者所施加的效应不同.
目的 探討遺忘型、非遺忘型輕度認知功能障礙(MCI)患者危險因素的差異. 方法 收集2011年1月至2011年9月于青島市市屬3傢三級醫院神經內科住院的65～75歲輕度認知功能障礙患者的健康資料,應用簡易智能狀態檢查量錶(MMSE)、矇特利爾認知評估量錶(MoCA)全麵評價患者的認知功能,採用Petersen標準將輕度認知功能障礙的患者分成遺忘型(aMCI)89例和非遺忘型(non-aMCI) 51例兩組,比較兩組患者的不同危險因素. 結果 aMCI和non-aMCI組患者的糖尿病(P=0.009)比例、高膽固醇(P=0.011)比例、MoCA評分(P=0.040)差異有統計學意義.aMCI組患者MoCA評分(OR=1.081,95％CI:1.001～1.204,P=0.040)明顯低于non-aMCI組；non-aMCI組糖尿病比例(OR=0.258,95％CI:0.096～0.695,P=0.009)明顯高于aMCI組；aMCI組高膽固醇比例(OR=13.345,95％CI:1.127～158.085,P=0.011)明顯高于non-aMCI組,且高膽固醇為aMCI的獨立危險因素. 結論 不同的危險因素對aMCI、non-aMCI患者所施加的效應不同.
목적 탐토유망형、비유망형경도인지공능장애(MCI)환자위험인소적차이. 방법 수집2011년1월지2011년9월우청도시시속3가삼급의원신경내과주원적65～75세경도인지공능장애환자적건강자료,응용간역지능상태검사량표(MMSE)、몽특리이인지평고량표(MoCA)전면평개환자적인지공능,채용Petersen표준장경도인지공능장애적환자분성유망형(aMCI)89례화비유망형(non-aMCI) 51례량조,비교량조환자적불동위험인소. 결과 aMCI화non-aMCI조환자적당뇨병(P=0.009)비례、고담고순(P=0.011)비례、MoCA평분(P=0.040)차이유통계학의의.aMCI조환자MoCA평분(OR=1.081,95％CI:1.001～1.204,P=0.040)명현저우non-aMCI조；non-aMCI조당뇨병비례(OR=0.258,95％CI:0.096～0.695,P=0.009)명현고우aMCI조；aMCI조고담고순비례(OR=13.345,95％CI:1.127～158.085,P=0.011)명현고우non-aMCI조,차고담고순위aMCI적독립위험인소. 결론 불동적위험인소대aMCI、non-aMCI환자소시가적효응불동.
Objective To explore the association of risk factors with amnestic versus nonamnestic of mild cognitive impairment.Methods All the subjects with mild cognitive impairment (MCI) aged 65-75 years were recruited from Neurology Department of 3 third-class hospitals of Qingdao,admitted from January 2011 to September 2011.They were systematically evaluated with mini-mental state examination( MMSE )and Montreal cognitive assessment (MoCA),then health conditions were collected.According to Petersen's standards,patients were divided into 89 cases with amnestic mild cognitive impairment(aMCI) and 51 cases with non-amnestic mild cognitive impairment (non-aMCI)groups to compare different risk factors between them.Results There were statistical differences in high total cholesterol (P=0.011),diabetes mellitus (P=0.009),MoCA score (P=0.040) between aMCI and non-aMCIgroups.MoCAscore (OR=1.081,95％CI:1.001-1.204,P=0.040) in the aMCI group was lower than that in non aMCI group.Diabetes mellitus ratio (OR=0.258,95％CI:0.096-0.695,P=0.009) was higher in non-aMCI group than in aMCI group.The level of total-cholesterol(OR=13.345,95％CI:1.127-158.085,P=0.011) in aMCI group was higher than that in non-aMCI group.The high total cholesterol was a independent risk factor for aMCI.Conclusions Different risk factors appear to exert different effects for aMCI and nonaMCI.
