CAJ | 학술논문

为了探讨白头翁复方对腹泻小鼠肠道粘膜乳糖酶活性的影响,取体重相近BALB/c小鼠180只,随机分预防组、治疗组、自愈组和对照组,每组45只,本试验采用Dahlqvist的方法测定各组小鼠前、中、后段肠道粘膜乳糖酶的活性.结果表明:预防组和治疗组乳糖酶的活性显著高于自愈组(P＜0.01),预防组和治疗组的差异不显著(P＞0.05).说明白头翁复方能够显著增强腹泻小鼠肠道粘膜上乳糖酶的活性,表明白头翁复方治疗腹泻的作用机理可能与调节乳糖酶的活性有关.
위료탐토백두옹복방대복사소서장도점막유당매활성적영향,취체중상근BALB/c소서180지,수궤분예방조、치료조、자유조화대조조,매조45지,본시험채용Dahlqvist적방법측정각조소서전、중、후단장도점막유당매적활성.결과표명:예방조화치료조유당매적활성현저고우자유조(P＜0.01),예방조화치료조적차이불현저(P＞0.05).설명백두옹복방능구현저증강복사소서장도점막상유당매적활성,표명백두옹복방치료복사적작용궤리가능여조절유당매적활성유관.
To investigate the regulatory effects of decoction of compound Radix pulsatillae on the activities of lactase in the intestinal mucosal cells of diarrheal mice,180 BALB/c mice were randomly divided into prevention group,treatment group,autotherapy group and control group with 45 mice in each group. The activities of lactase in the intestinal mucosal cells in diarrheal mice were determined by the modified method of Dahlqvis. The results showed as follows:the lactase activities of prevention group and treatment group were significantly higher than that of autotherapy group (P＜0.01). Prevention group and treatment group had no diversities. Decoction of compound Radix pulsatillae can treat diarrheal,and maybe this is caused by the activities of lactase.