CAJ | 학술논문

目的研究导入尿道支架技术的临床应用价值。方法治疗A组采用传统盲插法留置F18导尿管，留置不成功者即刻运用导入尿道支架技术重新留置改进的F18导尿管。治疗B组直接运用导入尿道支架技术留置改进的F18导尿管。两组患者均随访1年以上。结果 (1)一次置管成功率A组患者达48.98％ (24/49)，B组达97.94％(95/97)，B组显著高于A组，两组间差异具有统计学意义。(2)导管相关性尿路感染发生率A组为12.24％(6/49)，B组为8.25％(8/95)，两组差异具有统计学意义。(3)不良事件(导管腔堵塞、支架管脱出等)发生率A组8.33％(2/24)，B组发生率7.37％( 7/95)，两组差异无统计学意义；(4)治疗持续时间A组为46.2周，B组治疗持续时间为32.7周，两组差异有统计学意义。(5)尿道狭窄复发率A组为16.33％ (8/49)，B组尿道狭窄复发率为9.28％ (9/97)，两组差异有统计学意义。结论导入尿道支架技术置入成功率高，降低尿管相关性尿路感染发生率，为较长时间的尿道塑形提供了条件，降低了尿道再狭窄的发生率，缩短治疗周期。
목적 연구도입뇨도지가기술적림상응용개치。방법 치료A조채용전통맹삽법류치F18도뇨관，류치불성공자즉각운용도입뇨도지가기술중신류치개진적F18도뇨관。치료B조직접운용도입뇨도지가기술류치개진적F18도뇨관。량조환자균수방1년이상。결과 (1)일차치관성공솔A조환자체48.98％ (24/49)，B조체97.94％(95/97)，B조현저고우A조，량조간차이구유통계학의의。(2)도관상관성뇨로감염발생솔A조위12.24％(6/49)，B조위8.25％(8/95)，량조차이구유통계학의의。(3)불량사건(도관강도새、지가관탈출등)발생솔A조8.33％(2/24)，B조발생솔7.37％( 7/95)，량조차이무통계학의의；(4)치료지속시간A조위46.2주，B조치료지속시간위32.7주，량조차이유통계학의의。(5)뇨도협착복발솔A조위16.33％ (8/49)，B조뇨도협착복발솔위9.28％ (9/97)，량조차이유통계학의의。결론 도입뇨도지가기술치입성공솔고，강저뇨관상관성뇨로감염발생솔，위교장시간적뇨도소형제공료조건，강저료뇨도재협착적발생솔，축단치료주기。
Objective To improve the treatment of urethral stricture and evaluate the applicative effects of wire-guided supporting catheterization in clinical urology. Methods During January 2004 and December 2005, the patients with urethral stricture were dwelled with the catheters using the traditional guideless catheterization (group A). If the dwelling failed,it will be replaced by the wire-guided supporting catheterization using the improved catheters. During January 2006 and December 2009, the patients with urethral stricture were dwelled with the improved catheters using wire-guided supporting catheterization ( group B) straightly. Compared the first-time dwelling success incidence,the incidence of catheter associated urinary tract infection and side-effect events. Then after 1 year, compared the urethral stricture recrudescence and the course of treatment. Results The success incidence of first-time catheterization in group A was 48.98％ (24/49) ,and in group B was 97.94％ (95/97) ,there was significant difference between 2 groups;The incidence of catheter associated urinary tract infection in group A was 12.24％, and 8. 25％ in group B, there was significant difference between 2 groups; As for the course of treatment, group A was 46. 2w,group B was 32.7w;The urethral stricture recrudescence in group A and B were 16.33％ and 9.28％ respectively,and there was significant difference between 2 groups. Conclusion The wire-guided supporting catheterization, which minimize the injury and simplify the operation of internal urethrotomy,could makes the improved catheter easy to induct and replace, improve the success rate of first time-catheterization and prevent the false tunnel damage and new scar expansion. It could make benefit to reduce of incidence of catheter associated urinary tract infection and urethral stricture recrudescence,but also could shorten the course of treatment significantly.