中华肺部疾病杂志（电子版）
中華肺部疾病雜誌（電子版）
중화폐부질병잡지（전자판）
CHINESE JOURNAL OF LUNG DISEASE（ELECTRONIC EDITION）
2011年
3期
230-234
,共5页
呼吸机相关性肺炎%病原菌%耐药性
呼吸機相關性肺炎%病原菌%耐藥性
호흡궤상관성폐염%병원균%내약성
Ventilator-associated pneumonia%Pathogenic bacterium%Drug resistance
目的 探讨ICU呼吸机相关性肺炎病原菌的分布及其耐药性,为临床防治提供依据.方法 对2008年1月至2010年12月ICU呼吸机相关性肺炎患者下呼吸道痰液标本分离出的病原菌及其药敏试验结果进行回顾性分析.结果 共检出致病菌198株,其中革兰氏阴性菌131株,以鲍氏不动杆菌和铜绿假单胞菌为主;革兰氏阳性菌49株,以金黄色葡萄球菌为主,其中耐MRSA29株,耐药率为60%;真菌18株,全部为白色假丝酵母菌.革兰氏阴性菌均呈现多耐药性.讨论 ICU呼吸机相关性肺炎病原菌以革兰氏阴性菌为主且多药耐药,MRSA感染率高,合理使用抗菌药物已成为当务之急.
目的 探討ICU呼吸機相關性肺炎病原菌的分佈及其耐藥性,為臨床防治提供依據.方法 對2008年1月至2010年12月ICU呼吸機相關性肺炎患者下呼吸道痰液標本分離齣的病原菌及其藥敏試驗結果進行迴顧性分析.結果 共檢齣緻病菌198株,其中革蘭氏陰性菌131株,以鮑氏不動桿菌和銅綠假單胞菌為主;革蘭氏暘性菌49株,以金黃色葡萄毬菌為主,其中耐MRSA29株,耐藥率為60%;真菌18株,全部為白色假絲酵母菌.革蘭氏陰性菌均呈現多耐藥性.討論 ICU呼吸機相關性肺炎病原菌以革蘭氏陰性菌為主且多藥耐藥,MRSA感染率高,閤理使用抗菌藥物已成為噹務之急.
목적 탐토ICU호흡궤상관성폐염병원균적분포급기내약성,위림상방치제공의거.방법 대2008년1월지2010년12월ICU호흡궤상관성폐염환자하호흡도담액표본분리출적병원균급기약민시험결과진행회고성분석.결과 공검출치병균198주,기중혁란씨음성균131주,이포씨불동간균화동록가단포균위주;혁란씨양성균49주,이금황색포도구균위주,기중내MRSA29주,내약솔위60%;진균18주,전부위백색가사효모균.혁란씨음성균균정현다내약성.토론 ICU호흡궤상관성폐염병원균이혁란씨음성균위주차다약내약,MRSA감염솔고,합리사용항균약물이성위당무지급.
Objective To study the pathogenic bacteria distrbution and the drug resistance in vensive-care unit (ICU),so as to provide evidence for clinical prevention and treatment. Methods The distibution of isolated pathogenic bacteria and the drug sensivity results of patients with ventilator associated pneumonia(VAP) in ICU in Jan.2008-Dec.2010 were analyzed retrospectively. Results From 198 strains of pathogens 131 were Gram-negative bacteria accountea for 66.2% and showed the multi-drug resistance, of which Acinetobacter baumannii 20.1% and Pseudomonas aeruginosa 16.9%, were common Gram-positive bacteria (49 strains) accountea for 24.7%, the majority was Staphyloccus aureus 14.1, and 29 strains of MRSA fungi (18 strains) accounted for 9.1% all were Candida albicans. Conclusions The Gram-negative bacteria is the majority of pathogenic bacteria in VAP in ICU and showed the multi-drug resistance ,The infection rate of MRSA is high and it is urgent to make the rational application of antibiotics.
