CAJ | 학술논문

目的通过功能磁共振成像(functional magnetic resonance imaging,fMRI)技术研究健康人脑处理数字短时记忆的的脑区激活情况.方法 12名右利手健康被试者进行一项数字短时记忆任务作业的同时进行fMRI扫描,试验采用组块设计并采用统计参数图(SPM99)软件进行数据分析和脑功能区定位.结果 12名被试者数字短时记忆任务的正确率为(86.74±6.36)%.组分析统计阈值设定为P<0.0001时,大脑皮层所激活的脑区有双侧枕叶、额叶、顶叶,皮层下结构有纹状体的激活;其中双侧枕叶的激活最为显著.结论人脑处理数字短时记忆信息是由大脑皮层下结构与大脑皮层一起共同完成的,并以语音和视觉双重编码.
목적 통과공능자공진성상(functional magnetic resonance imaging,fMRI)기술연구건강인뇌처리수자단시기억적적뇌구격활정황.방법 12명우리수건강피시자진행일항수자단시기억임무작업적동시진행fMRI소묘,시험채용조괴설계병채용통계삼수도(SPM99)연건진행수거분석화뇌공능구정위.결과 12명피시자수자단시기억임무적정학솔위(86.74±6.36)%.조분석통계역치설정위P<0.0001시,대뇌피층소격활적뇌구유쌍측침협、액협、정협,피층하결구유문상체적격활;기중쌍측침협적격활최위현저.결론 인뇌처리수자단시기억신식시유대뇌피층하결구여대뇌피층일기공동완성적,병이어음화시각쌍중편마.
Objective To examine the activation of brain regions in normal volunteers during short-term digital memory task by functional magnetic resonance imaging(fMRI)technique.Methods 12 right-handed normal volunteers participated in a test of short-term digital memory task.while the fMRI data were recorded.A control task was performed for the block-design.SPM 99(statistics parameter mapping 99)was used to analyze the data and to get the activated brain regions.Results When the threshold of the group analysis was set as P＜0.0001,both cortex and subcortical structures were activated.The brain cortex areas including the bilateral occipital lobes,frontal lobes and parietal lobes were activated during the task.The subcortical structures including the lentiform nucleus and the caudate nucleus were also activated during the task.Meanwhile,the bilateral occipital lobes were the most prominently activated brain regions.Conclusion In human brain,the information of the short-term digital memois manipulated by the collaborative activity between subcortical stmctures and cortex and employing phonological and visual coding.