国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2010年
1期
31-35
,共5页
心率变异性%心肌缺血%符号动力学%自主神经系统
心率變異性%心肌缺血%符號動力學%自主神經繫統
심솔변이성%심기결혈%부호동역학%자주신경계통
Heart rate variability%Myocardial ischemia%Symbolic dynamics analysis%Autonomic nervous system
目的 基于心率变异性(HRV)研究,分析心肌缺血发生过程中心率的动态变化特性以探讨自主神经活动的变化和影响.方法 从长时ST段-T波终点(Long-term ST-T)数据库中,选取13个记录中共193个心肌缺血时段及其前后各5 min的对照时段.选用符号动力学方法分析不同时段的RR间期序列,利用重复测量的方差分析对缺血前和缺血中以及缺血后结果进行检验;以线性拟合的方式,分析心肌缺血时自主神经响应模式随缺血持续时间的分布.结果 较之心肌缺血前后,心肌缺血过程中0 V%的显著增加和2UV%的显著减小反映了交感神经活性的增加和迷走神经活性的减弱,但这种自丰神经平衡向交感神经更占优移动的趋势随着缺血持续时间的延长而减小,提示可能存在的对心脏的保护作用.结论 符号动力学分析为研究心肌缺血中自主神经的调制提供了一个敏感的工具.
目的 基于心率變異性(HRV)研究,分析心肌缺血髮生過程中心率的動態變化特性以探討自主神經活動的變化和影響.方法 從長時ST段-T波終點(Long-term ST-T)數據庫中,選取13箇記錄中共193箇心肌缺血時段及其前後各5 min的對照時段.選用符號動力學方法分析不同時段的RR間期序列,利用重複測量的方差分析對缺血前和缺血中以及缺血後結果進行檢驗;以線性擬閤的方式,分析心肌缺血時自主神經響應模式隨缺血持續時間的分佈.結果 較之心肌缺血前後,心肌缺血過程中0 V%的顯著增加和2UV%的顯著減小反映瞭交感神經活性的增加和迷走神經活性的減弱,但這種自豐神經平衡嚮交感神經更佔優移動的趨勢隨著缺血持續時間的延長而減小,提示可能存在的對心髒的保護作用.結論 符號動力學分析為研究心肌缺血中自主神經的調製提供瞭一箇敏感的工具.
목적 기우심솔변이성(HRV)연구,분석심기결혈발생과정중심솔적동태변화특성이탐토자주신경활동적변화화영향.방법 종장시ST단-T파종점(Long-term ST-T)수거고중,선취13개기록중공193개심기결혈시단급기전후각5 min적대조시단.선용부호동역학방법분석불동시단적RR간기서렬,이용중복측량적방차분석대결혈전화결혈중이급결혈후결과진행검험;이선성의합적방식,분석심기결혈시자주신경향응모식수결혈지속시간적분포.결과 교지심기결혈전후,심기결혈과정중0 V%적현저증가화2UV%적현저감소반영료교감신경활성적증가화미주신경활성적감약,단저충자봉신경평형향교감신경경점우이동적추세수착결혈지속시간적연장이감소,제시가능존재적대심장적보호작용.결론 부호동역학분석위연구심기결혈중자주신경적조제제공료일개민감적공구.
Objective To investigate the autonomic modulation and influence during myocardial ischemia based on analysis on heart rate dynamics with heart rate variability(HRV). Methods From 13 free download ECG records in long-term ST-T(LTST)database, 193 ischemia episodes were extracted for analysis, and 5 min intervals before and after each selected isehemia episode were selected as control ones. Using symbolic dynamic analysis method, the indexes during different stages were calculated. The repeated measurement analysis of variance was introduced for statistic test. And the distribution of autonomic reflex mode to isehemia duration was analyzed by linear fitting. Results Symbolic analysis detected an increase in the percentage of non-varlable patterns (0 V%) and a decrease in the percentage of very variable patterns(2 UV%), indicating a more sympathetic predominance compared with the baseline. But the trend of the shift in autonomic balance towards sympathetic predominance reduced with the extension of ischemic duration, suggesting a possible protection for heart. Conclusion Symbolic dynamic analysis is capable of identifying changes in autonomic modulation and seems appropriate for elucidating the neural pathophysiological mechanisms occurring in myocardial ischemic episodes.
