CAJ | 학술논문

目的了解男男性行为人群(MSM)HIV感染状况,探索感染的危险因素.方法采用同伴驱动抽样和滚雪球方法在北京市、哈尔滨市、郑州市与成都市招募MSM研究对象(1950名),以面对面问卷调查(共调查1950份,有效问卷1950份)获得相关人口学及行为学资料,抽取1950名调查对象各5 ml静脉血进行HIV抗体血清学检测(用胶体金法、乳胶层析法与双抗原夹心酶联免疫法进行初筛,用免疫印迹试验进行确证检测),描述HIV感染特征,分析其危险因素.对不同组别间的率或构成比进行x2检验,感染危险因素进行多因素logistic回归分析.结果共调查MSM 1864名,HⅣ感染率为6.7%(125/1864).≥40岁者HIV感染率为9.5%(24/252),≤19岁者为1.9%(2/105);大学文化程度者HIV感染率为4.8%(41/858),初中及以下文化程度者为8.4%(31/371);性伴与之年龄差小于10岁者为5.0%(58/1168),性伴比之大10岁者为10.3%(35/340);无无保护被动肛交者HIV感染率为5.5%(64/1169),有无保护被动肛交者为8.9%(61/695).年龄≥40岁(OR=6.5,95% CI:1.5～28.7)、初中及以下文化程度(OR=1.8,95% CI:1.1～2.7)、拥有比自己年龄大10岁及以上性伴(OR=2.1,95% CI:1.3～3.3)、有无保护被动肛交(OR=1.6,95% CI:1.1～2.4)是HIV感染的独立危险因素.结论 MSM人群HIV感染率较高,年龄大、文化程度低、拥有较大年龄的性伴及无保护被动肛交与HIV感染相关.
목적 료해남남성행위인군(MSM)HIV감염상황,탐색감염적위험인소.방법 채용동반구동추양화곤설구방법재북경시、합이빈시、정주시여성도시초모MSM연구대상(1950명),이면대면문권조사(공조사1950빈,유효문권1950빈)획득상관인구학급행위학자료,추취1950명조사대상각5 ml정맥혈진행HIV항체혈청학검측(용효체금법、유효층석법여쌍항원협심매련면역법진행초사,용면역인적시험진행학증검측),묘술HIV감염특정,분석기위험인소.대불동조별간적솔혹구성비진행x2검험,감염위험인소진행다인소logistic회귀분석.결과 공조사MSM 1864명,HⅣ감염솔위6.7%(125/1864).≥40세자HIV감염솔위9.5%(24/252),≤19세자위1.9%(2/105);대학문화정도자HIV감염솔위4.8%(41/858),초중급이하문화정도자위8.4%(31/371);성반여지년령차소우10세자위5.0%(58/1168),성반비지대10세자위10.3%(35/340);무무보호피동항교자HIV감염솔위5.5%(64/1169),유무보호피동항교자위8.9%(61/695).년령≥40세(OR=6.5,95% CI:1.5～28.7)、초중급이하문화정도(OR=1.8,95% CI:1.1～2.7)、옹유비자기년령대10세급이상성반(OR=2.1,95% CI:1.3～3.3)、유무보호피동항교(OR=1.6,95% CI:1.1～2.4)시HIV감염적독립위험인소.결론 MSM인군HIV감염솔교고,년령대、문화정도저、옹유교대년령적성반급무보호피동항교여HIV감염상관.
Objectives To access the prevalence of HIV infection and the associated factors among urban MSM in China. Methods Participants were recruited using respondent driven sampling and snowball sampling method in Beijing, Harbin, Zhengzhou and Chengdu city. A face-to-face questionnaire was administrated to collect relevant demographic and ethological data;5 ml venous blood sample was taken from each subject to measure HIV antibody in serum ( samples were first screened by colloidal gold, latex chromatographic and double-antigen sandwich ELISA method, positive samples were further confirmed by immunoblotting method ). The characteristics of HIV infection was described and the risk factors wereanalyzed. Results A total of 1864 MSM were recruited and the prevalence of HIV was 6.7% (125/1864).It was 9.5% (24/252) among MSM older than 39 years and it was 1.9% (2/105) among those less than 20 years old. The prevalence was 8.4% (31/371) among MSM with junior level education and was 4.8% (41/858) among those with college level education. It was 10.3% (35/340) among MSM with sexual partner old than him for over 10 years while it was 5.0% (58/1168) among those having sexual partner within 10 years older. The prevalence of HIV infection was 8.9% ( 61/695 ) among MSM with unprotected receptive anal sex and it was 5.5% (64/1169) among those without unprotected receptive anal sex. The risk factors independently associated with HIV infection included being older than 39 years( OR =6.5,95% CI:1.5 - 28.7 ), with junior or lower level education ( OR = 1.8,95% CI: 1.2 - 2.7 ), having sexual partner older than himself for over 10 years ( OR = 2.1,95% CI: 1.3 - 3.3 ) and having unprotected receptive anal intercourse( OR = 1.6,95% CI: 1.1 - 2.4). Conclusion MSM had a high rate of HIV infection. Older age,lower level education, having older sexual partner and unprotected receptive anal intercourse were related to HIV infection.