CAJ | 학술논문

目的:分析羟基磷灰石(hydroxyapatite,HA)义眼台眶内植入术后结膜脓性肉芽肿形成的原因.方法:回顾性分析我院眶内植入HA义眼台250例(钻孔及栓钉置入68例),随诊18mo～10a,脓性肉芽肿形成后首先药物保守治疗,无效后采用手术治疗.结果:植入HA义眼台250例中发生脓性肉芽肿10例,其中9例在钻孔及栓钉置入术4～7a后发生,1例发生时羟基磷灰石义眼台未钻孔.9例保守治疗效果均欠佳,行HA义眼台取出术,1例拒绝眼台取出而继续保守治疗. 结论:脓性肉芽肿是严重的义眼台植入术后并发症,发生原因可能与义眼台植入后血管化不足,义眼台暴露与继发感染,异体材料包被,义眼台钻孔及栓钉置入等因素有关,而与栓钉的材料无关.脓性肉芽肿的发生意味着义眼台可能发生了感染,最终需行义眼台取出术.
목적:분석간기린회석(hydroxyapatite,HA)의안태광내식입술후결막농성육아종형성적원인.방법:회고성분석아원광내식입HA의안태250례(찬공급전정치입68례),수진18mo～10a,농성육아종형성후수선약물보수치료,무효후채용수술치료.결과:식입HA의안태250례중발생농성육아종10례,기중9례재찬공급전정치입술4～7a후발생,1례발생시간기린회석의안태미찬공.9례보수치료효과균흠가,행HA의안태취출술,1례거절안태취출이계속보수치료. 결론:농성육아종시엄중적의안태식입술후병발증,발생원인가능여의안태식입후혈관화불족,의안태폭로여계발감염,이체재료포피,의안태찬공급전정치입등인소유관,이여전정적재료무관.농성육아종적발생의미착의안태가능발생료감염,최종수행의안태취출술.
AIM: To study the causes of pyogenic granuloma after hydroxyapatite(HA) orbital implants.METHODS: HA orbital implants (250 cases) in our hospital (68 pegged implants) were reviewed.All patients were followed up from 18 months to 10 years. Implants were removed after medical therapy which was proved to be ineffective.RESULTS: Ten of 250 cases of HA orbital implants developed pyogenic granuloma. Pyogenic granuloma occurred in 1 unpegged implants patient and 9 patients after pegging and drilling of HA implantation over 4～7 years. The pyogenic granulomas were not controlled by medical therapy effectively. Implants were removed in 9 cases except 1 case denied removing and continued medical therapy.CONCLUSION: Pyogenic granuloma was serious complication that occurred after HA orbital implants. Partial vascularization, implant exposure, xenogenic sclera implant, pegging and drilling of HA implantation are risk factors that affect the development of pyogenic granuloma.Pyogenic granuloma hasn't relation with implanted peg material. Pyogenic granuloma denotes the potential implant infection, and all implants should be removed finally.