中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2010年
5期
529-530
,共2页
马清君%冷青%季征%张桂敏%吴音
馬清君%冷青%季徵%張桂敏%吳音
마청군%랭청%계정%장계민%오음
环孢素A%CAG方案%骨髓增生异常综合征
環孢素A%CAG方案%骨髓增生異常綜閤徵
배포소A%CAG방안%골수증생이상종합정
Cyclosporin A%CAG regiment%Myelodysplastic syndrome
目的 分析环孢素A(CsA)联合CAG方案[粒细胞集落刺激因子(G-CSF)+阿糖胞苷(Ara-C)阿柔比星(ACLA)]治疗中高危低增生性骨髓增生异常综合征(hypo-MDS)的临床疗效.方法 应用CsA联合CAG方案治疗17例中高危hypo-MDS患者,随诊观察有效率及副作用发生情况.结果 治疗后有效率为82.4%(14/17),全部患者未发现严重毒副作用.结论 CsA联合CAG方案治疗中高危hypo-MDS患者安全、有效,但其长期疗效需进一步观察.
目的 分析環孢素A(CsA)聯閤CAG方案[粒細胞集落刺激因子(G-CSF)+阿糖胞苷(Ara-C)阿柔比星(ACLA)]治療中高危低增生性骨髓增生異常綜閤徵(hypo-MDS)的臨床療效.方法 應用CsA聯閤CAG方案治療17例中高危hypo-MDS患者,隨診觀察有效率及副作用髮生情況.結果 治療後有效率為82.4%(14/17),全部患者未髮現嚴重毒副作用.結論 CsA聯閤CAG方案治療中高危hypo-MDS患者安全、有效,但其長期療效需進一步觀察.
목적 분석배포소A(CsA)연합CAG방안[립세포집락자격인자(G-CSF)+아당포감(Ara-C)아유비성(ACLA)]치료중고위저증생성골수증생이상종합정(hypo-MDS)적림상료효.방법 응용CsA연합CAG방안치료17례중고위hypo-MDS환자,수진관찰유효솔급부작용발생정황.결과 치료후유효솔위82.4%(14/17),전부환자미발현엄중독부작용.결론 CsA연합CAG방안치료중고위hypo-MDS환자안전、유효,단기장기료효수진일보관찰.
Objective To observe the clinical effect of cyclosporin A (CsA) with CAG regiment on moderate- or high-risk hypoplastic myelodysplastic syndrome (hypo-MDS).Methods Senventeen moderate- or high-risk hypo-MDS patients receiving CsA with CAG regiment treatment were followed up to observe the effectiveness and incidence of adverse reactions.Results The total effective rate of 17 patients was 82.4%(14/17).No serious side effects were noted.Conclusion The combined CsA and CAG regiment treatment is safe,effective in treatment of moderate- or high-risk hypo-MDS,but its long-term effective rate needs further observation.
