CAJ | 학술논문

反向疫苗技术是指利用基因组序列信息和生物信息学技术,快速识别和鉴定疫苗候选分子的一种新型疫苗研制技术.该技术已被成功用于筛选B型脑膜炎双球菌疫苗候选抗原,且在其他重要的人体病原体疫苗候选分子的筛选中也得到了成功的应用,提示反向疫苗技术在新型疫苗研发中具有广阔的应用前景.
반향역묘기술시지이용기인조서렬신식화생물신식학기술,쾌속식별화감정역묘후선분자적일충신형역묘연제기술.해기술이피성공용우사선B형뇌막염쌍구균역묘후선항원,차재기타중요적인체병원체역묘후선분자적사선중야득도료성공적응용,제시반향역묘기술재신형역묘연발중구유엄활적응용전경.
Reverse vaceinology is a new technique in development of vaccine that makes use of the information of genome sequences and bioinformatics to identify candidate vaccines quickly.This approach has been successfully applied to the identification of meningococcus B as potential candidates,and other important human pathogens.It reveals that reverse vaccinology has wide prospect of application in the research and development of new vaccines.