中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
28期
12-14
,共3页
肺肿瘤%放射性核素显像%肿瘤转移
肺腫瘤%放射性覈素顯像%腫瘤轉移
폐종류%방사성핵소현상%종류전이
Lung neoplasms%Radionuclide imaging%Neoplasm metastasis
目的 分析肺癌核素骨显像的影像特征,评估单光子发射计算机断层显像术(SPECT)放射性核素骨显像诊断肺癌骨转移的临床价值.方法 177例确诊为肺癌的患者进行99mTc-MDP骨显像检查,对骨转移的症状、部位、数量与病理类型进行回顾性分析.结果 肺癌骨转移发生率为45.8%(81/177),其中多发性骨转移69例,占骨转移者的85.2%(69/81).腺癌骨转移发生率为69.0%(40/58),鳞癌为41.3%(19/46),小细胞癌为32.5%(13/40),未分化癌为27.3%(9/33),腺癌骨转移发生率与其他类型癌骨转移发生率比较差异有统计学意义(P＜0.05);共发现转移灶526处,部位以胸部为最多,共212处(40.3%),其他依次为脊柱168处(31.9%)、盆腔73处(13.9%)、四肢62处(11.8%)、颅骨11处(2.1%).结论 肺癌骨转移以多发病灶较为常见,部位以胸部、脊柱多发.腺癌骨转移发生率最高.肺癌患者应常规进行放射性核素骨显像,这对疾病的分期、治疗方案的选择、预后评估均有重要意义.
目的 分析肺癌覈素骨顯像的影像特徵,評估單光子髮射計算機斷層顯像術(SPECT)放射性覈素骨顯像診斷肺癌骨轉移的臨床價值.方法 177例確診為肺癌的患者進行99mTc-MDP骨顯像檢查,對骨轉移的癥狀、部位、數量與病理類型進行迴顧性分析.結果 肺癌骨轉移髮生率為45.8%(81/177),其中多髮性骨轉移69例,佔骨轉移者的85.2%(69/81).腺癌骨轉移髮生率為69.0%(40/58),鱗癌為41.3%(19/46),小細胞癌為32.5%(13/40),未分化癌為27.3%(9/33),腺癌骨轉移髮生率與其他類型癌骨轉移髮生率比較差異有統計學意義(P＜0.05);共髮現轉移竈526處,部位以胸部為最多,共212處(40.3%),其他依次為脊柱168處(31.9%)、盆腔73處(13.9%)、四肢62處(11.8%)、顱骨11處(2.1%).結論 肺癌骨轉移以多髮病竈較為常見,部位以胸部、脊柱多髮.腺癌骨轉移髮生率最高.肺癌患者應常規進行放射性覈素骨顯像,這對疾病的分期、治療方案的選擇、預後評估均有重要意義.
목적 분석폐암핵소골현상적영상특정,평고단광자발사계산궤단층현상술(SPECT)방사성핵소골현상진단폐암골전이적림상개치.방법 177례학진위폐암적환자진행99mTc-MDP골현상검사,대골전이적증상、부위、수량여병리류형진행회고성분석.결과 폐암골전이발생솔위45.8%(81/177),기중다발성골전이69례,점골전이자적85.2%(69/81).선암골전이발생솔위69.0%(40/58),린암위41.3%(19/46),소세포암위32.5%(13/40),미분화암위27.3%(9/33),선암골전이발생솔여기타류형암골전이발생솔비교차이유통계학의의(P＜0.05);공발현전이조526처,부위이흉부위최다,공212처(40.3%),기타의차위척주168처(31.9%)、분강73처(13.9%)、사지62처(11.8%)、로골11처(2.1%).결론 폐암골전이이다발병조교위상견,부위이흉부、척주다발.선암골전이발생솔최고.폐암환자응상규진행방사성핵소골현상,저대질병적분기、치료방안적선택、예후평고균유중요의의.
Objective To explore radionuclide bone imaging characteristics of lung cancer patients and evaluate the clinical significance of bone imaging in the diagnosis of lung cancer patients with bone metastases.Methods One hundred and seventy-seven patients with diagnosed lung cancer were examined by 99mTc -MDP bone imaging,and the symptoms,sites,quantity and pathological types of bone metastases were reviewed and analyzed.Results Total bone metastases ratio of lung cancer was 45.8%(81/177),and 85.2 % (69/81) patients had multiple bone metastases.There was a statistical significance of bone metastases in adenocarcinoma patients (69.0%,40/58),compared with patients of other types of lung cancer[squamous cell cancer (41.3%,19/46),small cell cancer ( 32.5%,13/40),undifferentiated carcinoma ( 27.3%,9/33)](P＜0.05).Bone metastases happened in 526 places: thoracic bones 212 places (40.3%),vertebras 168 places (31.9%),pelvic bones 73 places (13.9%),extremities 62 places (11.8%),and skull 11 places (2.1%).Conclusions Multiple bone metastases is more frequent in lung cancer patients.The most frequent metastatic sites are thoracic bones and vertebras.Bone metastases of adenocarcinoma is more easily than other types of lung cancer.All the patients with lung cancer should perform radionuclide bone scan,which is significant for staging,selecting therapy methods and the evaluating prognosis of the disease.
