CAJ | 학술논문

目的通过扰结核药联合糖皮质激素对结核菌素(PPD)试验阳性的结节性红斑的治疗,探讨结节性红斑可能诱因和临床特点.方法回顾性分析45例结核菌素试验阳性的结节性红斑的临床和实验室资料.结果 45例患者均具有典型的结节性红斑皮损,PPD试验阳性或强阳性(100%);男女之比为1:4.5,平均年龄34.5岁,平均病程1.2年.45例X光胸片检查合并肺结核6例(13.4%),淋巴结核4例(8.9%),胸膜炎4例(8.9%),肺部阴影灶8例(17.8%),无异常者23例(51%);实验检查:45例中血沉增快32例,抗"O"阳性2例,IgG较正常升高3例,类风湿因子阳性2例,痰菌涂片阳性1例,其余各项均为阴性.结论结节性红斑病因复杂,结核菌感染是主要诱因,对结核菌素试验阳性的结节性红斑,抗结核药联合糖皮质激素治疗有良好的临床疗效.
목적 통과우결핵약연합당피질격소대결핵균소(PPD)시험양성적결절성홍반적치료,탐토결절성홍반가능유인화림상특점.방법 회고성분석45례결핵균소시험양성적결절성홍반적림상화실험실자료.결과 45례환자균구유전형적결절성홍반피손,PPD시험양성혹강양성(100%);남녀지비위1:4.5,평균년령34.5세,평균병정1.2년.45례X광흉편검사합병폐결핵6례(13.4%),림파결핵4례(8.9%),흉막염4례(8.9%),폐부음영조8례(17.8%),무이상자23례(51%);실험검사:45례중혈침증쾌32례,항"O"양성2례,IgG교정상승고3례,류풍습인자양성2례,담균도편양성1례,기여각항균위음성.결론 결절성홍반병인복잡,결핵균감염시주요유인,대결핵균소시험양성적결절성홍반,항결핵약연합당피질격소치료유량호적림상료효.
Objective Through treating with antituberculoties and glucocorticoids, explore the pos-sible motivation and clinical features of erythema nodosum in tuberculin (PPD) test-positive patients Methods Clinical and laboratory data of 45 cases of erythema nodosum were retrospective analyzed, Results 45 patients had typical erytbema nodosum lesions and PPD test-positive or strong positive (100%). According to the chest X-ray examination, 6 cases (13.4%) were with pulmonary tuberculosis, 4 cases(8.9%) with lymph node nuclear, 4 cases (8.9%) with pleurisy, 8 cases (17.8%) with lung shadow foci and 23 cases (51%) have no abnormalities. The results of experimental examination showed that 32 cases were with faster blood sedimentation rate, 2 cases with anti-"O" positive, three cases with IgG higher than the normal, 2 cases with rheumatoid factor positive, one case expectoration bacterium film preparation positive and the rest were all negative. Conclusion The etiology of erythema nodosum was complex and mycobacterium tuberculosis infection was one of the major motivations of tuberculin test-positive erythema nodesum. The treatment of patients with antituberculotics and glucocorticoids could receive good clinical therapeutic effect.