CAJ | 학술논문

目的调查中国自然人群下肢外周动脉疾病(peripheral arterial disease,PAD)患病率及相关危险因素,为开展下肢动脉粥样硬化的预防提供科学依据.方法采用分层整群随机抽样的方法,选取北京、上海、长沙、广东、内蒙古和新疆地区的社区自然人群作为研究对象,由培训过的医师对调查对象进行踝臂指数(ankle brachial index,ABI)测量和资料收集.任一侧肢体ABI≤0.9诊断为PAD.结果在21 152例受试者中,PAD患病率3.08%,标化患病率3.04%;男性PAD患病率2.52%,标化患病率1.84%;女性PAD患病率3.66%,标化患病率4.31%,男性PAD患病率低于女性(P<O.01).男女PAD患病率均随着年龄的增加而明显升高(P<O.01).不同民族的PAD患病率差异较大,汉族居民患病率3.31%,高于维吾尔族、蒙古族及其他民族患病率(P<0.01).经logistic 回归分析发现,年龄、性别(女性)、民族(汉族)、腹围、吸烟、血脂异常、糖尿病、冠心病、缺血性脑卒中史等因素或共患疾病与PAD患病有关.在PAD患者中,仅1.38%有PAD诊断史.结论在中国自然人群中,年龄、性别(女性)、民族(汉族)、腹围、吸烟、血脂异常、糖尿病、冠心病、缺血性脑卒中史等因素或共患疾病与PAD患病有关.
목적 조사중국자연인군하지외주동맥질병(peripheral arterial disease,PAD)환병솔급상관위험인소,위개전하지동맥죽양경화적예방제공과학의거.방법 채용분층정군수궤추양적방법,선취북경、상해、장사、엄동、내몽고화신강지구적사구자연인군작위연구대상,유배훈과적의사대조사대상진행과비지수(ankle brachial index,ABI)측량화자료수집.임일측지체ABI≤0.9진단위PAD.결과 재21 152례수시자중,PAD환병솔3.08%,표화환병솔3.04%;남성PAD환병솔2.52%,표화환병솔1.84%;녀성PAD환병솔3.66%,표화환병솔4.31%,남성PAD환병솔저우녀성(P<O.01).남녀PAD환병솔균수착년령적증가이명현승고(P<O.01).불동민족적PAD환병솔차이교대,한족거민환병솔3.31%,고우유오이족、몽고족급기타민족환병솔(P<0.01).경logistic 회귀분석발현,년령、성별(녀성)、민족(한족)、복위、흡연、혈지이상、당뇨병、관심병、결혈성뇌졸중사등인소혹공환질병여PAD환병유관.재PAD환자중,부1.38%유PAD진단사.결론 재중국자연인군중,년령、성별(녀성)、민족(한족)、복위、흡연、혈지이상、당뇨병、관심병、결혈성뇌졸중사등인소혹공환질병여PAD환병유관.
Objective To investigate the prevalence of peripheral arterial disease (PAD) and correlative risk factors among natural population in China. Methods Ankle brachial index ( ABI) was measured by trained doctors and related data were collected in residents from Beijing, Shanghai, Changsha, Guangdong, Neimenggu, and Xinjiang selected through cluster multistage and random sampling method. PAD was defined as an ABI ≤ 0. 9 in either leg. Results The prevalence of PAD among 21 152 eligible participants was 3. 08% , the standardized prevalence was 3. 04%. The prevalence in males and females was 2. 52% and 3. 66% and the standardized prevalence was 1. 84% and 4. 31% respectively, the prevalence rate was significantly lower in males than that in females (P < 0. 01). The prevalence in both males and females increased significantly in proportion to aging ( P < 0. 01 ) . The prevalence in Han Chinese was significantly higher than that in non-Han Chinese ( P < 0. 01). Logistic regression analysis showed that older age, female gender, Han Chinese, waist circumference, smoking, lipid disorder, diabetes mellitus, coronary artery disease and a history of ischemic stroke were associated with the increased prevalence of PAD. Incidence of known PAD was 1.38% in this cohort. Conclusions Older age, female gender, Han Chinese, waist circumference, smoking, lipid disorder, diabetes mellitus, coronary artery disease and a history of ischemic stroke were associated with the increased prevalence of PAD in natural Chinese population.