CAJ | 학술논문

目的探讨CT影像在肺泡蛋白沉积症(PAP)临床疗效判定中的价值.方法回顾性分析9例PAP患者肺泡灌洗前后胸部CT影像资料、肺功能检查结果及血气分析检测指标;在CT图像上对病变范围进行影像学量化评分,并与肺功能及血气分析指标进行相关性分析.结果 9例PAP患者肺泡灌洗前胸部CT具有特征性影像表现,病变范围量化评分与肺总量(TLC)、用力呼吸肺活量(FVC)、一氧化碳弥散量(D_LCO)、动脉血氧分压(PaO_2)和动脉血氧饱和度(SaO_2)呈显著负相关,P值均<0.05.肺泡灌洗后肺功能各项指标均有不同程度改善,PaO2、SaO2较灌洗前明显增加.结论胸部CT检查可为PAP临床诊断、治疗及预后评估提供客观依据.
목적 탐토CT영상재폐포단백침적증(PAP)림상료효판정중적개치.방법 회고성분석9례PAP환자폐포관세전후흉부CT영상자료、폐공능검사결과급혈기분석검측지표;재CT도상상대병변범위진행영상학양화평분,병여폐공능급혈기분석지표진행상관성분석.결과 9례PAP환자폐포관세전흉부CT구유특정성영상표현,병변범위양화평분여폐총량(TLC)、용력호흡폐활량(FVC)、일양화탄미산량(D_LCO)、동맥혈양분압(PaO_2)화동맥혈양포화도(SaO_2)정현저부상관,P치균<0.05.폐포관세후폐공능각항지표균유불동정도개선,PaO2、SaO2교관세전명현증가.결론 흉부CT검사가위PAP림상진단、치료급예후평고제공객관의거.
Objective To study the value of chest CT in evaluating the curative effect for pulmonary alveolar proteinosis (PAP). Methods The chest CT findings and the results of pulmonary function tests and blood gas analysis in 9 patients with PAP before and after bronchoalveolar lavage (BAL) were reviewed retrospectively. The lesions in extent were scored on CT images. The relationship between the imaging scores and pulmonary function tests as well as blood gas were analysed. Results The results of pulmonary function tests such as TLC,PVC,PEV_1 and D_LCO were improved to a certain degree after BAL in 9 patients with PAP; PaO_2 and SaO_2 were increased significantly after BAL(P<0. 05). CT scores before BAL correlated significantly with TLC , PVC , D_LCO , PaO_2 and SaO_2 (P<0. 05). Conclusion CT examination can provide objective imformations for clinical diagnosis, treatment and prognostic evaluation of pulmonary alveolar proteinosis.