中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
8期
1143-1144
,共2页
美托洛尔%硝苯地平治%无症状性心肌缺血
美託洛爾%硝苯地平治%無癥狀性心肌缺血
미탁락이%초분지평치%무증상성심기결혈
Metoprolol%Nifedipine treatment%Silent myocardial ischemia
目的 探讨美托洛尔与硝苯地平治疗老年人无症状性心肌缺血的临床应用价值.方法 选择56例无症状性心肌缺血老年患者,随机数字表法分为美托洛尔组和硝苯地平组各28例.分析两组治疗期间并发症发生情况、治疗前后发作次数及发作时间.结果 美托洛尔组与硝苯地平组患者治疗前发作次数分别为(19.6±3.2)次/周与(18.9±2.8)次/周,发作时间(5131±352)s与(5130±348)s,差异均无统计学意义(均P＞0.05)；治疗后发作次数分别为(4.6±2.1)次/周与(7.4±2.1)次/周,发作时间(900±140)s与(1440±240)s,差异均有统计学意义(均P＜0.05).所有患者治疗期间均能耐受,无心肌梗死病例出现.结论 美托洛尔与硝苯地平对于老年人无症状性心肌缺血的治疗较为安全,美托洛尔较硝苯地平治疗效果好.
目的 探討美託洛爾與硝苯地平治療老年人無癥狀性心肌缺血的臨床應用價值.方法 選擇56例無癥狀性心肌缺血老年患者,隨機數字錶法分為美託洛爾組和硝苯地平組各28例.分析兩組治療期間併髮癥髮生情況、治療前後髮作次數及髮作時間.結果 美託洛爾組與硝苯地平組患者治療前髮作次數分彆為(19.6±3.2)次/週與(18.9±2.8)次/週,髮作時間(5131±352)s與(5130±348)s,差異均無統計學意義(均P＞0.05)；治療後髮作次數分彆為(4.6±2.1)次/週與(7.4±2.1)次/週,髮作時間(900±140)s與(1440±240)s,差異均有統計學意義(均P＜0.05).所有患者治療期間均能耐受,無心肌梗死病例齣現.結論 美託洛爾與硝苯地平對于老年人無癥狀性心肌缺血的治療較為安全,美託洛爾較硝苯地平治療效果好.
목적 탐토미탁락이여초분지평치료노년인무증상성심기결혈적림상응용개치.방법 선택56례무증상성심기결혈노년환자,수궤수자표법분위미탁락이조화초분지평조각28례.분석량조치료기간병발증발생정황、치료전후발작차수급발작시간.결과 미탁락이조여초분지평조환자치료전발작차수분별위(19.6±3.2)차/주여(18.9±2.8)차/주,발작시간(5131±352)s여(5130±348)s,차이균무통계학의의(균P＞0.05)；치료후발작차수분별위(4.6±2.1)차/주여(7.4±2.1)차/주,발작시간(900±140)s여(1440±240)s,차이균유통계학의의(균P＜0.05).소유환자치료기간균능내수,무심기경사병례출현.결론 미탁락이여초분지평대우노년인무증상성심기결혈적치료교위안전,미탁락이교초분지평치료효과호.
Objective To explore the clinical value of application of metoprolol and nifedipine in the treatment of asymptomatic myocardial ischemia for the elderly.Methods 56 cases of elderly patients with silent myocardial ischemia were chosen.They were randomly divideded into the metoprolol group of 28 cases and nifedipine group with 28 cases according to the number table.The incidence of complications during treatment in the metoprolol and nifedipine group were analyzed.The seizure frequency and onset time in the two groups of patients were compared before and after treatment.Results The onset time in the two groups,before treatment had no statistically significant difference[the number of attacks:(19.6±3.2) times/week compared with(18.9±2.8) times/week;attack time:(5131±352)s vs (5130 ± 348 ) s,all ( P ＞ 0.05 ).After treatment,there were statistically significant differences for the number of attacks and attack time [the number of attacks:(4.6 ± 2.1 ) times/week compared with ( 7.4 ± 2.1 )times/week,onset tine:(900 ± 140) s vs ( 1440 ± 240 ) s ( all P ＜ 0.05 ).All patients can tolerate the treatment period,there was no cases of myocardial infarction occurs.Conclusion The metoprolol and nifedipine for the elderly treatment of silent myocardial ischemia was more secure,and metoprolol was more effective than nifedipine.
