中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
7期
894-895
,共2页
宫腔镜%体外受精-胚胎移植%官腔病变
宮腔鏡%體外受精-胚胎移植%官腔病變
궁강경%체외수정-배태이식%관강병변
Hysteroscopy%In vitro fertilization-embryo transfer%Uterine-cavity lesion
目的 探讨官腔镜在体外受精.胚胎移植(IVF-ET)失败后再次行辅助技术治疗中的应用价值.方法 随机抽取IVF-ET失败后准备再次治疗的患者167例,根据有否行宫腔镜检查分为观察组97例,对照组70例.再根据宫腔镜检查结果分为宫腔异常组和宫腔正常组.比较观察组与对照组、异常组与正常组再次IVF-ET的临床妊娠率.分析不同宫腔疾患经纠正治疗后再次IVF-ET的效果.结果 官腔异常率44.3% (43/97),主要是微小病变,包括:子宫内膜息肉、内膜炎、子宫黏膜下小肌瘤、官腔轻度粘连、子宫内膜单纯增 生过长及息肉样增生.再次IVF-ET临床妊娠率:观察组与对照组分别为35.1%、22.9%;官腔异常组与宫腔正常组分别为48.1%、24.1%,差异均有统计学意义(均P<0.05).经宫腔镜处理治疗后,子宫内膜息肉、子宫黏膜下小肌瘤、子宫内膜息肉样增生、内膜单纯性增生过长的临床妊娠率高于宫腔粘连及子宫内膜炎,分别为75.0%、100.0%、66.7%、50.0%、11.1%、33.3%.结论 宫腔镜能准确诊断处理宫内微小病变,提高再次IVF-ET的临床妊娠率.
目的 探討官腔鏡在體外受精.胚胎移植(IVF-ET)失敗後再次行輔助技術治療中的應用價值.方法 隨機抽取IVF-ET失敗後準備再次治療的患者167例,根據有否行宮腔鏡檢查分為觀察組97例,對照組70例.再根據宮腔鏡檢查結果分為宮腔異常組和宮腔正常組.比較觀察組與對照組、異常組與正常組再次IVF-ET的臨床妊娠率.分析不同宮腔疾患經糾正治療後再次IVF-ET的效果.結果 官腔異常率44.3% (43/97),主要是微小病變,包括:子宮內膜息肉、內膜炎、子宮黏膜下小肌瘤、官腔輕度粘連、子宮內膜單純增 生過長及息肉樣增生.再次IVF-ET臨床妊娠率:觀察組與對照組分彆為35.1%、22.9%;官腔異常組與宮腔正常組分彆為48.1%、24.1%,差異均有統計學意義(均P<0.05).經宮腔鏡處理治療後,子宮內膜息肉、子宮黏膜下小肌瘤、子宮內膜息肉樣增生、內膜單純性增生過長的臨床妊娠率高于宮腔粘連及子宮內膜炎,分彆為75.0%、100.0%、66.7%、50.0%、11.1%、33.3%.結論 宮腔鏡能準確診斷處理宮內微小病變,提高再次IVF-ET的臨床妊娠率.
목적 탐토관강경재체외수정.배태이식(IVF-ET)실패후재차행보조기술치료중적응용개치.방법 수궤추취IVF-ET실패후준비재차치료적환자167례,근거유부행궁강경검사분위관찰조97례,대조조70례.재근거궁강경검사결과분위궁강이상조화궁강정상조.비교관찰조여대조조、이상조여정상조재차IVF-ET적림상임신솔.분석불동궁강질환경규정치료후재차IVF-ET적효과.결과 관강이상솔44.3% (43/97),주요시미소병변,포괄:자궁내막식육、내막염、자궁점막하소기류、관강경도점련、자궁내막단순증 생과장급식육양증생.재차IVF-ET림상임신솔:관찰조여대조조분별위35.1%、22.9%;관강이상조여궁강정상조분별위48.1%、24.1%,차이균유통계학의의(균P<0.05).경궁강경처리치료후,자궁내막식육、자궁점막하소기류、자궁내막식육양증생、내막단순성증생과장적림상임신솔고우궁강점련급자궁내막염,분별위75.0%、100.0%、66.7%、50.0%、11.1%、33.3%.결론 궁강경능준학진단처리궁내미소병변,제고재차IVF-ET적림상임신솔.
Objective To investigate the applied value of hysteroscopy in in vitro fertilization-embryo transfer (IVF-ET) after recurrent 1VF-ET failures.Methods 167 patients who had been recurrent failure in IVF-ET were randomly enrolled in this research.They were divided into 97 cases of study group and 70 cases of control group.According to the results of the hysteroscopy, the study group included the normal uterine cavity and abnormal uterine cavity.The clinical results were compared in study group and control group, abnormal group and normal group.The clinical results were analyzed after treatment of abnormal uterine cavity.Results Abnormal rate of hysteroscopy was 44.3% (43/97) ,the abnormality were mainly minimal lesions including endometrial polyps, endometritis.submucous myoma,endometrial adhesion, simple and polypoid hyperplasia of endometium.After another IVF-ET, The pregnant rate were significantly different(35.1% vs 22.9% ) between study group and control group,and significantly different (48.1 % vs 24.1 % ) between abnormal group and normal group(all P < 0.05).After treatment, the pregnant rate was higher in endometrial polyps (75.0% ), submucous myoma (100.0% ), simple polypoid hyperplasia of endometium (66.7% ) .simple hyperplasia(50.0% ) than endometrial adhesion(11.1% ) and endometritis(33.3% ).Conclusion Hysteroscopy can accurately diagnose lesions in uterine cavity and increase clinical pregnant rate in IVF-ET.