CAJ | 학술논문

目的了解健康人群肝炎病毒感染现状.方法采用ELISA方法检测体检人群血清中抗甲(HAV-IgG)、乙(HBsAg和HBsAb)、丙(HCV-IgG)和戊型肝炎病毒抗体(HEV-IgG和IgM).人群血清均收集于2007年.结果 1352份人群血清肝炎病毒抗体阳性率,HAV-IgG为81,07%(1096/1352),HBsAg和HBsAb为5.4%(73/1352)和61.32%(829/1352),HCV-IgG为0.37%(5/1352),HEV-IgG为49.26%(666/1352).不同年龄段的人群HAV-IgG阳性率,10～19岁组为38.21%,20～29岁组为83%,30～39岁组为88%,40岁以上各年龄组为95.03%～97.77%.HBsAg和HBsAb阳性率,各年龄组依次为5.65%和50.83%、10.0%和68.0%、5.20%和78.80%、5.97%和78.11%、6.50%和62.50%、1.12%和51.40%、4.96%和30.58%.HCV-IgG阳性总数5份,其中10～19岁组1份,阳性率占0.33%,30～39岁组2份,占0.80%,60～69岁1份占0.56%,≥70岁1份占0.83%.HEV-IgG阳性率,10～19岁为26.58%,20～29岁组为42.0%,30岁以上各年龄组阳性率为55.22%～61.0%.对HEV-IgG阳性者再检测HEV-IgG,总阳性率为10.06%(53/527),各年龄组均有阳性者.结论青少年HAV和HBsAb抗体低于人群总体水平,应及时加强免疫预防.人群HBsAg和HCV感染率与往年相比下降明显.HEV感染率随年龄增长而升高,特别是各年龄段均有新近感染者,应加强餐饮和公共卫生管理.
목적 료해건강인군간염병독감염현상.방법 채용ELISA방법검측체검인군혈청중항갑(HAV-IgG)、을(HBsAg화HBsAb)、병(HCV-IgG)화무형간염병독항체(HEV-IgG화IgM).인군혈청균수집우2007년.결과 1352빈인군혈청간염병독항체양성솔,HAV-IgG위81,07%(1096/1352),HBsAg화HBsAb위5.4%(73/1352)화61.32%(829/1352),HCV-IgG위0.37%(5/1352),HEV-IgG위49.26%(666/1352).불동년령단적인군HAV-IgG양성솔,10～19세조위38.21%,20～29세조위83%,30～39세조위88%,40세이상각년령조위95.03%～97.77%.HBsAg화HBsAb양성솔,각년령조의차위5.65%화50.83%、10.0%화68.0%、5.20%화78.80%、5.97%화78.11%、6.50%화62.50%、1.12%화51.40%、4.96%화30.58%.HCV-IgG양성총수5빈,기중10～19세조1빈,양성솔점0.33%,30～39세조2빈,점0.80%,60～69세1빈점0.56%,≥70세1빈점0.83%.HEV-IgG양성솔,10～19세위26.58%,20～29세조위42.0%,30세이상각년령조양성솔위55.22%～61.0%.대HEV-IgG양성자재검측HEV-IgG,총양성솔위10.06%(53/527),각년령조균유양성자.결론 청소년HAV화HBsAb항체저우인군총체수평,응급시가강면역예방.인군HBsAg화HCV감염솔여왕년상비하강명현.HEV감염솔수년령증장이승고,특별시각년령단균유신근감염자,응가강찬음화공공위생관리.
Objective To investigate the seroprevulence of hepatitis viruses in Mianyang of the Sichuan province. Methods EIISA was used for detecting anti-HAV IgG,HBsAg/HBsAb,anti-HCV IgG and anti-HEV IgG of the serum samples. All sample were collected in Mianyang areas in 2007. Results 1352 samples were detected. The positive rates of anti-HAY,HBsAg/HBsAb,anti-HCV,and anti-HEV are 81.07 % (1096/1352),5.40% (73/ 1352) and 61.32% (829/1352),0.37% (5/1352) and 49.26% (666/1352),respectively. The positive rate at different age group,for anti-HAV was 38.21%of 10-19 years old,83% of 20-29 years old,88% of 30-39 years old,95.03% of 40-49 years old,97% of 50-59 years old,97.77% of 60-69 years old,97.52% of ≥70 years old. For HBsAg/HBsAb were 5.65% or 50.83%,10.0% or 68.0%,5.20% or 78.80%,5.97% or 78.11%,6.50% or 62.50% ,1.12% or 51.40% ,4.96% or 30.58% at the same age group,respectively,for anti-HCV,was 0.33% of 10-19 yaers old,0.80% of 30-39 years,O.56% of 60-69 years old,0.83% of ≥70 years old. For HEV-IgG was 26.58% of 10-19 years old,42.0%of 20-29 years old,55.22%-61.0% of 30≥70 years old,for anti-HEV IgM ,was 10.06% (53/527) in the positive samples of HEV-IgG. Conclusion The inoculation againt HAV and HBV is enhanced in the young population. HBsAg carrier and HCV infection is decreasing. The HEY infection is actually increasing.