CAJ | 학술논문

目的探讨前白蛋白(PA)在手足口病病情监测及预后中的应用价值.方法检测390例患儿治疗过程中及治疗前后血清PA水平,比较其在治疗过程中的变化,并观察病例预后情况.结果病情加重组PA在第1～7天持续降低,第7天与第1和3天比较差异显著(t值分别为14.073和11.104,均P<0.01).PA水平与SPAS Ⅱ评分间呈明显负相关(r=-0.564,P<0.01).结论 PA水平在手足口患儿经有效治疗后可发生显著变化,PA检测对手足口病预后观察具有重要临床意义.
목적 탐토전백단백(PA)재수족구병병정감측급예후중적응용개치.방법 검측390례환인치료과정중급치료전후혈청PA수평,비교기재치료과정중적변화,병관찰병례예후정황.결과 병정가중조PA재제1～7천지속강저,제7천여제1화3천비교차이현저(t치분별위14.073화11.104,균P<0.01).PA수평여SPAS Ⅱ평분간정명현부상관(r=-0.564,P<0.01).결론 PA수평재수족구환인경유효치료후가발생현저변화,PA검측대수족구병예후관찰구유중요림상의의.
Objective To explore the curative effect of prealbumin (PA) in the hand-foot-and-mouth dis-ease and analysis its value in monitoring and prognosing this disease. Method Detect levels of serum PA of 390 ca-ses of children before, after and during the treatment and compare the changes during the treatment. Then observe the prognosis. Results There are significant difference of PV levels between cases of different prognosis (P < 0.05). Conclusion The PV levels of children of hand-foot-and-mouth disease will change significantly after effective treat- ment. There are clinical significance in observing and prognosing the hand-foot-and-mouth disease by detecting the se-rum PV levels.