CAJ | 학술논문

目的探讨原发性高血压与血清C反应蛋白(CRP)和血脂水平的关系.方法 186例原发性高血压患者按高血压水平分为A组85例(1级高血压)、B组65例(2级高血压)、C组36例(3级高血压),另选同期健康体检者66例为D组,比较各组CRP、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平.结果 A、B、C组CRP、TC、TG、HDL-C、LDL-C水平与D组比较差异均有统计学意义(均P＜0.05),A、B、C三组间各项指标差异均有统计学意义,且三组CRP水平与TG、TC、HDL-C、LDL-C水平有明显相关性(均P＜0.05).结论高血压水平与患者血清CRP及血脂水平具有明显相关性.
목적 탐토원발성고혈압여혈청C반응단백(CRP)화혈지수평적관계.방법 186례원발성고혈압환자안고혈압수평분위A조85례(1급고혈압)、B조65례(2급고혈압)、C조36례(3급고혈압),령선동기건강체검자66례위D조,비교각조CRP、총담고순(TC)、감유삼지(TG)、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)수평.결과 A、B、C조CRP、TC、TG、HDL-C、LDL-C수평여D조비교차이균유통계학의의(균P＜0.05),A、B、C삼조간각항지표차이균유통계학의의,차삼조CRP수평여TG、TC、HDL-C、LDL-C수평유명현상관성(균P＜0.05).결론 고혈압수평여환자혈청CRP급혈지수평구유명현상관성.
Objective To investigate the relationship between essential hypertension and serum C-reactive protein and plasma lipids.Methods Detecting fasting serum CRP and plasma lipid in each group of hypertensive patients to investigate the relationship between hypertension and fasting serum CRP and plasma lipids.Results CRP,TC,TG,HDL-C and LDL-C level of A,B and C group had significant differences with that of D group(t =4.03, 4.23, 4.61, 3.12, 3.41, 2.76,2.98,2.56,2.64,2.57,3.05,3.68,2.54,3.16,4.28,all P＜0.05).CRP,TC,TG,HDL-C and LDL-C levels between A,B and C group had significant differences(F = 4.68,4.05,3.29,3.59,4.11,all P＜0.05).There was significant correlation between serum CRP level and TC,TG,HDL-C,LDL-C level in 186 hypertension patients(r =0.274,0.356,0.327,0.302,all P＜0.05).Conclusion CRP,TC,TG and LDL-C levels showed significant linear correlation in patients with hypertension.