中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
2期
196-197
,共2页
紫癜,过敏性%一清胶囊%头孢克洛
紫癜,過敏性%一清膠囊%頭孢剋洛
자전,과민성%일청효낭%두포극락
Purpura,schoenlein-henoch%Yiqing capsules%Cefaclor
目的 评价-清胶囊联合头孢克洛治疗单纯型过敏性紫癜患者的临床疗效.方法 随机、单盲、对照临床试验,入组191例单纯型过敏性紫癜患者,咽部分泌物A组乙型溶血链球菌抗原检测均为阳性.对照组92例口服头孢克洛片和常规治疗,治疗组99例在对照组基础上口服一清胶囊.结果 治疗10 d后,治疗组、对照组有效率分别为91.9%、75.0%,治疗组有效率明显高于对照组(P＜0.01);咽拭子复检阴转率,治疗组、对照组阴转率分别为96.0%、87.0%,治疗组咽拭子复检阴转率明显高于对照组(P＜0.01);治疗组起效时间明显早于对照组(P＜0.01);3个月复发率,治疗组低于对照组(P＜0.05).结论 一清胶囊联合头孢克洛治疗单纯型过敏性紫癜,能提高疗效,缩短治疗时间.
目的 評價-清膠囊聯閤頭孢剋洛治療單純型過敏性紫癜患者的臨床療效.方法 隨機、單盲、對照臨床試驗,入組191例單純型過敏性紫癜患者,嚥部分泌物A組乙型溶血鏈毬菌抗原檢測均為暘性.對照組92例口服頭孢剋洛片和常規治療,治療組99例在對照組基礎上口服一清膠囊.結果 治療10 d後,治療組、對照組有效率分彆為91.9%、75.0%,治療組有效率明顯高于對照組(P＜0.01);嚥拭子複檢陰轉率,治療組、對照組陰轉率分彆為96.0%、87.0%,治療組嚥拭子複檢陰轉率明顯高于對照組(P＜0.01);治療組起效時間明顯早于對照組(P＜0.01);3箇月複髮率,治療組低于對照組(P＜0.05).結論 一清膠囊聯閤頭孢剋洛治療單純型過敏性紫癜,能提高療效,縮短治療時間.
목적 평개-청효낭연합두포극락치료단순형과민성자전환자적림상료효.방법 수궤、단맹、대조림상시험,입조191례단순형과민성자전환자,인부분비물A조을형용혈련구균항원검측균위양성.대조조92례구복두포극락편화상규치료,치료조99례재대조조기출상구복일청효낭.결과 치료10 d후,치료조、대조조유효솔분별위91.9%、75.0%,치료조유효솔명현고우대조조(P＜0.01);인식자복검음전솔,치료조、대조조음전솔분별위96.0%、87.0%,치료조인식자복검음전솔명현고우대조조(P＜0.01);치료조기효시간명현조우대조조(P＜0.01);3개월복발솔,치료조저우대조조(P＜0.05).결론 일청효낭연합두포극락치료단순형과민성자전,능제고료효,축단치료시간.
Objective To investigate the efficacy of Yiqing capsules and Cefaclortablets in the treatment of simplex anaphylactoid purpura. Methods In this randomized,simple-blind, controlled study, all of 191 simplex anaphylactoid purpura patients,the throat secretion Group A βhemolytic streptococci antigen test was positive ,92 patients of control group were treated Cefaclor tablets and regular treatment,99 patients of test group were Yiqing capsules and Cefaclor tablets. Results After 10 days treatment,the clinical efficacy of the test group and the control group were 91.9% ,75.0% ,the test group was obviously higher than that of the control group(P ＜ 0.01), and the negative rate of the throat secretion Group A βhemolytic Streptococci antigen test of the test group was higher than that of control group, (P ＜0.01). the commencements of response of the test group was earlier than that of the control group(P ＜0. 01) ,the frequencies of recurrence of the test group were lower than that of the control group (P ＜ 0. 05).Conclusion Yiqing capsules combined cefaclor in treatment of simplex allergic purpura could improve efficacy, and reduce the treatment time.
