中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2011年
2期
133-137
,共5页
杨琪放%张挽时%孟利民%时惠平%王东%毕永民%李相生%方红%郭和清%严景民
楊琪放%張輓時%孟利民%時惠平%王東%畢永民%李相生%方紅%郭和清%嚴景民
양기방%장만시%맹이민%시혜평%왕동%필영민%리상생%방홍%곽화청%엄경민
尿路结石%体层摄影术,X线计算机
尿路結石%體層攝影術,X線計算機
뇨로결석%체층섭영술,X선계산궤
Urinary calculi%Tomography,X-ray computed
目的 评价双源CT双能量成像区分泌尿系统结石成分的应用价值.方法 对97枚经内镜碎石后取出的泌尿系统结石行双源CT双能量扫描.以红外光谱仪测定的结石成分为参考标准,将结石分为6组:尿酸结石组、胱氨酸结石组、磷酸镁铵结石组、草酸钙结石组、混合尿酸结石组和混合含钙结石组.测量计算80和140 kV结石的HU差值、HU比值和双能量指数(DEI),并采用方差分析比较上述指标的差异.使用双能量软件定性诊断结石成分,并与红外光谱仪测定的成分结果比较.结果 尿酸结石组(10枚)、胱氨酸结石组(5枚)、磷酸镁铵结石组(6枚)、草酸钙结石组(22枚)、混合尿酸结石组(7枚)和混合含钙结石组(47枚)的HU差值分别为(-17±13)、(229±34)、(309±45)、(512±97)、(201±64)和(530±71)HU,HU比值分别为0.96±0.03、1.34±0.04、1.41±0.03、1.47±0.03、1.30±0.07和1.49±0.03,DEI分别为-0.006±0.004、0.064±0.007、0.080±0.007、0.108±0.011、0.055±0.014和0.112±0.008,差异有统计学意义(F值分别为124.894、407.028、322.864,P值均＜0.01).尿酸结石组与其他结石组HU差值、HU比值和DEI差异有统计学意义(P值均＜0.01).草酸钙结石组、混合含钙结石组分别与其他4组结石HU差值、HU比值和DEI差异有统计学意义(P值均＜0.01).胱氨酸结石组与磷酸镁铵结石组HU比值差异有统计学意义(P＜0.01).磷酸镁铵结石组与混合尿酸结石组HU差值、HU比值和DEI差异有统计学意义(P值均＜0.05).双能量软件正确定性诊断10枚尿酸结石、4枚胱氨酸结石、22枚草酸钙结石和6枚混合尿酸结石.2枚磷酸镁铵结石被诊断为含胱氨酸成分.1枚胱氨酸结石、1枚混合尿酸结石、4枚磷酸镁铵结石和47枚混合含钙结石被诊断为含草酸盐成分.结论 双源CT双能量成像对于区分泌尿系统结石成分有一定价值.双能量软件可以较好地区分尿酸结石、胱氨酸结石、混合尿酸结石与其他类型结石.
目的 評價雙源CT雙能量成像區分泌尿繫統結石成分的應用價值.方法 對97枚經內鏡碎石後取齣的泌尿繫統結石行雙源CT雙能量掃描.以紅外光譜儀測定的結石成分為參攷標準,將結石分為6組:尿痠結石組、胱氨痠結石組、燐痠鎂銨結石組、草痠鈣結石組、混閤尿痠結石組和混閤含鈣結石組.測量計算80和140 kV結石的HU差值、HU比值和雙能量指數(DEI),併採用方差分析比較上述指標的差異.使用雙能量軟件定性診斷結石成分,併與紅外光譜儀測定的成分結果比較.結果 尿痠結石組(10枚)、胱氨痠結石組(5枚)、燐痠鎂銨結石組(6枚)、草痠鈣結石組(22枚)、混閤尿痠結石組(7枚)和混閤含鈣結石組(47枚)的HU差值分彆為(-17±13)、(229±34)、(309±45)、(512±97)、(201±64)和(530±71)HU,HU比值分彆為0.96±0.03、1.34±0.04、1.41±0.03、1.47±0.03、1.30±0.07和1.49±0.03,DEI分彆為-0.006±0.004、0.064±0.007、0.080±0.007、0.108±0.011、0.055±0.014和0.112±0.008,差異有統計學意義(F值分彆為124.894、407.028、322.864,P值均＜0.01).尿痠結石組與其他結石組HU差值、HU比值和DEI差異有統計學意義(P值均＜0.01).草痠鈣結石組、混閤含鈣結石組分彆與其他4組結石HU差值、HU比值和DEI差異有統計學意義(P值均＜0.01).胱氨痠結石組與燐痠鎂銨結石組HU比值差異有統計學意義(P＜0.01).燐痠鎂銨結石組與混閤尿痠結石組HU差值、HU比值和DEI差異有統計學意義(P值均＜0.05).雙能量軟件正確定性診斷10枚尿痠結石、4枚胱氨痠結石、22枚草痠鈣結石和6枚混閤尿痠結石.2枚燐痠鎂銨結石被診斷為含胱氨痠成分.1枚胱氨痠結石、1枚混閤尿痠結石、4枚燐痠鎂銨結石和47枚混閤含鈣結石被診斷為含草痠鹽成分.結論 雙源CT雙能量成像對于區分泌尿繫統結石成分有一定價值.雙能量軟件可以較好地區分尿痠結石、胱氨痠結石、混閤尿痠結石與其他類型結石.
목적 평개쌍원CT쌍능량성상구분비뇨계통결석성분적응용개치.방법 대97매경내경쇄석후취출적비뇨계통결석행쌍원CT쌍능량소묘.이홍외광보의측정적결석성분위삼고표준,장결석분위6조:뇨산결석조、광안산결석조、린산미안결석조、초산개결석조、혼합뇨산결석조화혼합함개결석조.측량계산80화140 kV결석적HU차치、HU비치화쌍능량지수(DEI),병채용방차분석비교상술지표적차이.사용쌍능량연건정성진단결석성분,병여홍외광보의측정적성분결과비교.결과 뇨산결석조(10매)、광안산결석조(5매)、린산미안결석조(6매)、초산개결석조(22매)、혼합뇨산결석조(7매)화혼합함개결석조(47매)적HU차치분별위(-17±13)、(229±34)、(309±45)、(512±97)、(201±64)화(530±71)HU,HU비치분별위0.96±0.03、1.34±0.04、1.41±0.03、1.47±0.03、1.30±0.07화1.49±0.03,DEI분별위-0.006±0.004、0.064±0.007、0.080±0.007、0.108±0.011、0.055±0.014화0.112±0.008,차이유통계학의의(F치분별위124.894、407.028、322.864,P치균＜0.01).뇨산결석조여기타결석조HU차치、HU비치화DEI차이유통계학의의(P치균＜0.01).초산개결석조、혼합함개결석조분별여기타4조결석HU차치、HU비치화DEI차이유통계학의의(P치균＜0.01).광안산결석조여린산미안결석조HU비치차이유통계학의의(P＜0.01).린산미안결석조여혼합뇨산결석조HU차치、HU비치화DEI차이유통계학의의(P치균＜0.05).쌍능량연건정학정성진단10매뇨산결석、4매광안산결석、22매초산개결석화6매혼합뇨산결석.2매린산미안결석피진단위함광안산성분.1매광안산결석、1매혼합뇨산결석、4매린산미안결석화47매혼합함개결석피진단위함초산염성분.결론 쌍원CT쌍능량성상대우구분비뇨계통결석성분유일정개치.쌍능량연건가이교호지구분뇨산결석、광안산결석、혼합뇨산결석여기타류형결석.
Objective To evaluate dual-source dual-energy CT(DSCT) for the differentiation of urinary stone composition in vitro. Methods Ninety-seven urinary stones were obtained by endoscopic lithotripsy and scanned using dual-source dual-energy CT. The stones were divided into six groups according to infrared spectroscopy stone analysis: uric acid ( UA ) stones ( n = 10 ), cystine stones ( n = 5 ), struvite stones( n = 6), calcium oxalate ( CaOx ) stones ( n = 22 ), mixed UA stones ( n=7 ) and mixed calcium stones(n=47). Hounsfield units (HU) of each stone were recorded for the 80 kV and the 140 kV datasets by hand-drawing method. HU difference, HU ratio and dual energy index ( DEI ) were calculated and compared among the stone groups with one-way ANOVA. Using dual energy software to determine the composition of all stones, results were compared to infrared spectroscopy analysis. Results There were statistical differences in HU difference [(-17±13), (229±34),(309 ±45), (512 ±97), (201±64)and (530±71) HU respectively], in HU ratio (0.96±0.03, 1.34 ±0.04, 1.41 ±0.03, 1.47 ±0.03,1.30±0.07, and 1.49 ±0.03 respectively), and DEI( -0.006 ±0.004, 0.064 ±0.007, 0.080 ±0. 007, 0. 108±0.011 ,0. 055 ±0.014 and 0. 112 ±0.008 respectively ) among different stone groups(F=124. 894,407.028, 322. 864 respectively, P ＜0. 01 ). There were statistical differences in HU difference,HU ratio and DE1 between UA stones and the other groups( P ＜ 0. 01 ). There were statistical differences in HU difference, HU ratio and DEI between CaOx or mixed calcium stones and the other four groups (P＜0. 01 ). There was statistical difference in HU ratio between cystine and struvite stones ( P ＜ 0. 01 ). There were statistical differences in HU difference, HU ratio and DEI between struvite and mixed UA stones (P＜0. 05 ). Dual energy software correctly characterized 10 UA stones, 4 cystine stones, 22 CaOx stones and 6 mixed UA stones. Two struvite stones were considered to contain cystine. One cystine stone, 1 mixed UA stone, 4 struvite stones and 47 mixed calcium stones were considered to contain oxalate. Conclusions DSCT has the ability to differentiate urinary stone composition in vitro. With dual energy software, the UA, cystine and mixed UA stones can be differentiated from other types of stones.
