CAJ | 학술논문

目的探讨奥扎格雷钠联合阿司匹林肠溶片和低分子肝素钙治疗非ST段抬高型急性冠状动脉综合征疗效和安全性.方法 60例非ST段抬高型急性冠状动脉综合征患者完全随机分为2组,每组30例,治疗组给予奥扎格雷钠、阿司匹林肠溶片和低分子肝素钙三联治疗,对照组给予阿司匹林肠溶片和低分子肝素钙二联治疗,观察2组疗效和药物不良反应.结果治疗组治疗总有效27例(90.0%),较对照组22例(73.3%)高,差异有统计学意义(P<0.05);2组患者治疗前、后各项凝血指标及药物他不良反应情况比较,差异无统计学意义(P0.05).结论奥扎格雷钠、阿司匹林肠溶片和低分子肝素钙三联治疗非ST段抬高型急性冠状动脉综合征疗效较好且安全性良好.
목적 탐토오찰격뢰납연합아사필림장용편화저분자간소개치료비ST단태고형급성관상동맥종합정료효화안전성.방법 60례비ST단태고형급성관상동맥종합정환자완전수궤분위2조,매조30례,치료조급여오찰격뢰납、아사필림장용편화저분자간소개삼련치료,대조조급여아사필림장용편화저분자간소개이련치료,관찰2조료효화약물불량반응.결과 치료조치료총유효27례(90.0%),교대조조22례(73.3%)고,차이유통계학의의(P<0.05);2조환자치료전、후각항응혈지표급약물타불량반응정황비교,차이무통계학의의(P0.05).결론 오찰격뢰납、아사필림장용편화저분자간소개삼련치료비ST단태고형급성관상동맥종합정료효교호차안전성량호.
Objective To explore the efficacy and safety of a combination of sodium ozagrel, aspirin and low molecular heparin calcium for patients with NSTEACS. Methods A total of 30 patients received aspirin and low molecular heparin calcium and 30 received aspirin and low molecular heparin plus sodium ozagrel. Results The therapeutic effect in sodium ozagrel group was significandy better than in control group (P<0.05). All blood clotting indexes and adverse reactions showed no significant difference between the two groups (P 0. 05). Conclusion The combination of aspirin and low molecular heparin calcium plus sodium ozagrel showes better outcome and safety for patients with NSTEACS.