CAJ | 학술논문

目的：探讨早期应用中药针剂葛根素和脉安定防治急性心肌梗死(AMI)再灌注心律失常的效果。方法：对102例AMI患者随机分为中西药治疗组和西药治疗对照组，每组51例。中药治疗组采用针剂葛根素和脉安定静滴，对照组用极化液静滴；溶栓和其它治疗2组相同，均采用常规方法。结果：中西药治疗组心律失常较对照组显著减少(P<0.01)。综合评价中西药治疗组总有效率为96.1％，对照组为82.4％，2组有显著差异(P<0.01)。结论：葛根素和脉安定对AMI再灌注心律失常有明显的防治效果。
목적：탐토조기응용중약침제갈근소화맥안정방치급성심기경사(AMI)재관주심률실상적효과。방법：대102례AMI환자수궤분위중서약치료조화서약치료대조조，매조51례。중약치료조채용침제갈근소화맥안정정적，대조조용겁화액정적；용전화기타치료2조상동，균채용상규방법。결과：중서약치료조심률실상교대조조현저감소(P<0.01)。종합평개중서약치료조총유효솔위96.1％，대조조위82.4％，2조유현저차이(P<0.01)。결론：갈근소화맥안정대AMI재관주심률실상유명현적방치효과。
Objective:To investigate the preventive and therapeutic effects of puerarin(葛根素) and panangin(脉安定) early used on cardiac arrhythmia induced by reperfusion injury in patients with acute myocardial infarction(AMI).Methods:One hundred and two cases with AMI were randomly divided into two groups.The treatment group (n=51) was treated with puerarin injection and panangin infused intravenously,but the control group treated with compound of glucose-insulinpotassium.The thrombolytic and additional therapies were given to both groups simultaneously,the conventional therapy was given also to both groups.Results:The reperfusion arrhythmia(RA) was significantly decreased in treatment group compared to that in control group (P<0.01).The total effective rate was 96.1％ in treatment group and 82.4％ in control group.There was significantly different between two groups(P<0.01).Conclusions:The study indicates that puerarin and panangin has obviously preventive and therapeutic efficacy on cardiac arrhythmia induced by reperfusion injury in patients with AMI.