CAJ | 학술논문

目的:探讨高强度超声(High intensity ultrasound,HIU)切除离体人子宫内膜编的有效性及可行性.方法:收集人子宫内膜癌标本15例.用频率7.5MHz,声强50W/cm~2的超声进行辐照,每次辐照时间5秒至20秒,辐照后进行TTC染色及光镜下观察损伤范围及程度.结果:随着超声辐照时间的延长,损伤深度在逐渐增大,最大损伤深度可达到12mm,出现在单次辐照20秒;HIU辐照后的子宫内膜癌及其下部分肌层TTC染色不着色,辐照区内癌细胞发生凝固性坏死.结论:声强50W/cm~2的HIU能有效损伤离体子宫内膜癌,超声对子宫内膜癌的损伤深度与辐照时间有关.
목적:탐토고강도초성(High intensity ultrasound,HIU)절제리체인자궁내막편적유효성급가행성.방법:수집인자궁내막암표본15례.용빈솔7.5MHz,성강50W/cm~2적초성진행복조,매차복조시간5초지20초,복조후진행TTC염색급광경하관찰손상범위급정도.결과:수착초성복조시간적연장,손상심도재축점증대,최대손상심도가체도12mm,출현재단차복조20초;HIU복조후적자궁내막암급기하부분기층TTC염색불착색,복조구내암세포발생응고성배사.결론:성강50W/cm~2적HIU능유효손상리체자궁내막암,초성대자궁내막암적손상심도여복조시간유관.
Objeetive:To explore the effectiveness and the feasibility of high intensity ultrasound(HIU)ablation of human uterine endometrial carcinoma.Methods:Fifteen human uterine specimens with endometrial carcinoma were sonicated by HIU transducer with a frequency of 7.5 MHz and an intensity of 50W/cm~2,the exposure time was 5 to 20 seconds.Triphenyl tetrazolium chloride(TTC)staining and histological examination were carried out to evaluate the damage.Resets:The lesion depth was increased with the exposure time,the maximum lesion was 12mm in depth when sonicated for 20 seconds.Histological examination revealed coagulation necrosis and TTC staining was negative in the sonoablated endometrial carcinoma.Conclusion:HIU is competent in ablation of the uterine endometrial carcinoma,the depth of the lesion was relined to sonicated time.