中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2010年
9期
1599-1602
,共4页
老年人尸体%青年人尸体%脊柱%胸椎松质骨%冲击功%冲击韧性
老年人尸體%青年人尸體%脊柱%胸椎鬆質骨%遲擊功%遲擊韌性
노년인시체%청년인시체%척주%흉추송질골%충격공%충격인성
背景:骨质疏松、骨重建、骨再造、胸椎骨折固定器选择等都需要了解青年和老年尸体胸椎松质骨的冲击力学特性.以往的研究多以单独青年尸体或单独老年尸体胸椎松质骨为观察对象,而有关青年和老年尸体胸椎松质骨冲击力学特性的研究报道极少.目的:对正常国人青年和老年新鲜尸体胸椎松骨进行冲击实验,分析胸椎松质骨的冲击力学性质,确定老年尸体松质骨和青年尸体胸椎松质骨是否具有不同的冲击力学性质.方法:实验标本取自4具正常国人男性新鲜尸体,年龄分别为20,25,70,75岁,由白求恩医科大学解剖教研室提供.人死亡后1 h之内解剖取出死者胸椎T_(3~12)标本,将标本沿纵向切成长40 mm,宽6 mm,高6 mm的试样,每组各20个.以能量释放的方法对2组试样进行冲击实验,在室温28℃的温度场下进行实验.实验结束后,试验机测量度盘自动显示试样的冲击功,根据材料力学公式计算出每个试样的冲击韧性,观察各试样的宏观断口形貌.结果与结论:青年组胸椎松质骨冲击功、冲击韧性均显著大于老年组(P<0.05).胸椎松质骨冲击实验断口多数为粉碎性断口,少数为横断口或斜断口.宏观观察青年组腰椎松质骨骨小梁排列细密,老年组腰椎松质骨骨小梁排列稀疏,孔隙较大,呈现出老年骨质疏松的表现形式.提示青年组脊柱胸椎松质骨和老年组脊柱胸椎松质骨具有不同的冲击力学特性,老年组试样由于骨质疏松导致冲击力学特性发生改变.
揹景:骨質疏鬆、骨重建、骨再造、胸椎骨摺固定器選擇等都需要瞭解青年和老年尸體胸椎鬆質骨的遲擊力學特性.以往的研究多以單獨青年尸體或單獨老年尸體胸椎鬆質骨為觀察對象,而有關青年和老年尸體胸椎鬆質骨遲擊力學特性的研究報道極少.目的:對正常國人青年和老年新鮮尸體胸椎鬆骨進行遲擊實驗,分析胸椎鬆質骨的遲擊力學性質,確定老年尸體鬆質骨和青年尸體胸椎鬆質骨是否具有不同的遲擊力學性質.方法:實驗標本取自4具正常國人男性新鮮尸體,年齡分彆為20,25,70,75歲,由白求恩醫科大學解剖教研室提供.人死亡後1 h之內解剖取齣死者胸椎T_(3~12)標本,將標本沿縱嚮切成長40 mm,寬6 mm,高6 mm的試樣,每組各20箇.以能量釋放的方法對2組試樣進行遲擊實驗,在室溫28℃的溫度場下進行實驗.實驗結束後,試驗機測量度盤自動顯示試樣的遲擊功,根據材料力學公式計算齣每箇試樣的遲擊韌性,觀察各試樣的宏觀斷口形貌.結果與結論:青年組胸椎鬆質骨遲擊功、遲擊韌性均顯著大于老年組(P<0.05).胸椎鬆質骨遲擊實驗斷口多數為粉碎性斷口,少數為橫斷口或斜斷口.宏觀觀察青年組腰椎鬆質骨骨小樑排列細密,老年組腰椎鬆質骨骨小樑排列稀疏,孔隙較大,呈現齣老年骨質疏鬆的錶現形式.提示青年組脊柱胸椎鬆質骨和老年組脊柱胸椎鬆質骨具有不同的遲擊力學特性,老年組試樣由于骨質疏鬆導緻遲擊力學特性髮生改變.
배경:골질소송、골중건、골재조、흉추골절고정기선택등도수요료해청년화노년시체흉추송질골적충격역학특성.이왕적연구다이단독청년시체혹단독노년시체흉추송질골위관찰대상,이유관청년화노년시체흉추송질골충격역학특성적연구보도겁소.목적:대정상국인청년화노년신선시체흉추송골진행충격실험,분석흉추송질골적충격역학성질,학정노년시체송질골화청년시체흉추송질골시부구유불동적충격역학성질.방법:실험표본취자4구정상국인남성신선시체,년령분별위20,25,70,75세,유백구은의과대학해부교연실제공.인사망후1 h지내해부취출사자흉추T_(3~12)표본,장표본연종향절성장40 mm,관6 mm,고6 mm적시양,매조각20개.이능량석방적방법대2조시양진행충격실험,재실온28℃적온도장하진행실험.실험결속후,시험궤측량도반자동현시시양적충격공,근거재료역학공식계산출매개시양적충격인성,관찰각시양적굉관단구형모.결과여결론:청년조흉추송질골충격공、충격인성균현저대우노년조(P<0.05).흉추송질골충격실험단구다수위분쇄성단구,소수위횡단구혹사단구.굉관관찰청년조요추송질골골소량배렬세밀,노년조요추송질골골소량배렬희소,공극교대,정현출노년골질소송적표현형식.제시청년조척주흉추송질골화노년조척주흉추송질골구유불동적충격역학특성,노년조시양유우골질소송도치충격역학특성발생개변.
BACKGROUND:Impact mechanics properties of thoracic vertebra cancellous bone should be understood in treating osteoporosis,bone remodeling,bone reconstruction,as well as fixator selection for thoracic vertebral fracture.Most of previous studies concerning youth and the elderly bodies alone,reports regarding impact of thoracic vertebra cancellous bone mechanical properties are few.OBJECTIVE:To perform impact experiment to the normal people youth and the elderly fresh corpse thoracic vertebra cancellous bone to survey the impact mechanical properties,and to definite whether the impact mechanical properties of thoracic vertebra trabecular bone have difference between youth and the elderly people.METHODS:Experimental samples were from 4 normal fresh corpse,aged 20,25,70 and 75 years,were provided by Department of Anatomy,Norman Bethune Medical University.Spinal column thoracic vertebra T_(3-12) specimen were obtained from corpse within 1 hours and cut into 40 mm×6 mm×6 mm pieces,with 20 test pieces in each group.The impact experiment was performed using energy liberation method at room temperature under 28 ℃.After experiment,the impact energy was displayed automatic on testing machine,and the impact toughness was calculated by mechanical formula,and the morphology of fracture surface was observed.RESULTS AND CONCLUSION:The impact energy and impact toughness of the youth group was obviously greater than that of the elderly group (P<0.05).Majority of the fracture surfaces were comminuted,minority were transverse or oblique fracture.The macroscopic observation showed that trabecular arranged compact in the thoracic vertebra cancellous bone of the youth group,which was sparse arrangement and presented with senile osteoporosis in the elderly group.It demonstrated that the impact mechanics properties of thoracic vertebra cancellous bone are different between the youth and elderly groups,and osteoporosis changes impact mechanics properties in the elderly people.