第二军医大学学报
第二軍醫大學學報
제이군의대학학보
ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY
2008年
3期
233-235
,共3页
孙学军%John H Zhang
孫學軍%John H Zhang
손학군%John H Zhang
氢%抗氧化剂%再灌注损伤
氫%抗氧化劑%再灌註損傷
경%항양화제%재관주손상
hydrogen%antioxidants%reperfusion injury
最近Ohsawa等报道,呼吸氢气能通过抗氧化作用,减少动物脑和肝缺血再灌注引起的细胞凋亡.实际上,人和动物消化道内许多正常细菌能产生氢气,这些氢气可被消化道吸收进入血液循环.考虑到小鼠部分器官内氢气水平已达到产生抗氧化作用的浓度,我们认为,氢是一种内源性抗氧化物质.
最近Ohsawa等報道,呼吸氫氣能通過抗氧化作用,減少動物腦和肝缺血再灌註引起的細胞凋亡.實際上,人和動物消化道內許多正常細菌能產生氫氣,這些氫氣可被消化道吸收進入血液循環.攷慮到小鼠部分器官內氫氣水平已達到產生抗氧化作用的濃度,我們認為,氫是一種內源性抗氧化物質.
최근Ohsawa등보도,호흡경기능통과항양화작용,감소동물뇌화간결혈재관주인기적세포조망.실제상,인화동물소화도내허다정상세균능산생경기,저사경기가피소화도흡수진입혈액순배.고필도소서부분기관내경기수평이체도산생항양화작용적농도,아문인위,경시일충내원성항양화물질.
Recently,Ohsawa et al. provide evidence that inhaled hydrogen gas has antioxidant and antiapoptotic activities that protect the brain and liver against ischemia-reperfusion injury. In fact,there is some endogenous hydrogen produced by intestinal bacteria within animal and human.The concentration of hydrogen in some mice tissues reached the antioxidant effect in their paper demonstrates,so we think that hydrogen should be an endogenous antioxidant in the body.