CAJ | 학술논문

背景:骨水泥如果固化时间太快,黏度降低,应用时町能会使塑型困难.目的:检测在柠檬酸中添加壳聚糖、明胶配制的崮化液与á-磷酸三钙和羟桀磷灰石复合的粉剂调和制备骨水泥试样的性能.设计、时间及地点:开放性实验,于材料:将á-磷酸三钙粉末与羟基磷灰石粉末混合均匀制得骨水泥粉料,壳聚糖和明胶按不同比例与柠檬酸溶液混合配制的崮化液,然后二者调和制得骨水泥.方法:净浆稠度及凝结时间测定仪测定骨水泥的凝固时间,MTS-810型材料试验机测试各种配比骨水泥的压缩强度,打描电镜脱察固化体经37℃生理盐水浸渍2个月后的微观结构.主要观察指标:骨水泥的凝固时间及压缩强度,骨水泥水化反应的pH值及其微观结构.结果:调和液中添加的壳聚糖和明胶,使其黏度明显增加,固化时间延长,试样抗水冲性能提高,样品塑型容易操作,但试样抗压强度有所降低.骨水泥水化反应的pH值随着水化反应的进行逐渐上升,24 h时接近生理盐水的pH值.壳聚糖一明胶含量不同可以得到不同机械强度的á-磷酸三钙,羟基磷灰石两相骨水泥,骨水泥试样24 h基本达到最大强度,在48 h后强度几乎不再变化.结论:固化液中添加壳聚糖、明胶制备的á-磷酸三钙/羟基磷灰石两相骨水泥克服了陶瓷型羟基磷灰石烧结形成、修整困难等缺点,具有塑型容易、使用方便、固化时放热小等优点.
배경:골수니여과고화시간태쾌,점도강저,응용시정능회사소형곤난.목적:검측재저몽산중첨가각취당、명효배제적고화액여á-린산삼개화간걸린회석복합적분제조화제비골수니시양적성능.설계、시간급지점:개방성실험,우재료:장á-린산삼개분말여간기린회석분말혼합균균제득골수니분료,각취당화명효안불동비례여저몽산용액혼합배제적고화액,연후이자조화제득골수니.방법:정장주도급응결시간측정의측정골수니적응고시간,MTS-810형재료시험궤측시각충배비골수니적압축강도,타묘전경탈찰고화체경37℃생리염수침지2개월후적미관결구.주요관찰지표:골수니적응고시간급압축강도,골수니수화반응적pH치급기미관결구.결과:조화액중첨가적각취당화명효,사기점도명현증가,고화시간연장,시양항수충성능제고,양품소형용역조작,단시양항압강도유소강저.골수니수화반응적pH치수착수화반응적진행축점상승,24 h시접근생리염수적pH치.각취당일명효함량불동가이득도불동궤계강도적á-린산삼개,간기린회석량상골수니,골수니시양24 h기본체도최대강도,재48 h후강도궤호불재변화.결론:고화액중첨가각취당、명효제비적á-린산삼개/간기린회석량상골수니극복료도자형간기린회석소결형성、수정곤난등결점,구유소형용역、사용방편、고화시방열소등우점.
BACKGROUND:When bone cement solidifies fast,the bone cement consistency will be decreased.resulting in difficulty in molding.DESIGN,TIME AND SETTING:Open experiment,performed in the Laboratory of Department of Materials,Lanzhou Jiaotong University between March 2005 and August 2006.gelatin were mixed with citric acid to produce hardening liquid.Then bone cement power and hardening liquid were mixed to form a paste,I.e.,bone cement.METHODS:Setting time of bone cement was determined using a Vicat apparatus.The compressive strength of bone cement at different proportions was tested using MTS-810 material tester.After 2 months of physiological saline soaking at 37℃.the microstructure of solidified bone cement was observed using scanning electron microscope.MAIN OUTCOME MEASURES:Setting time and compressive strength of bone cement,pH value of hydrated bone cement and the microstructure.RESULTS:After adding chitosan and gelatin in the hardening liquid.the consistency of the concoction obviously increased,the setting time became a little longer and the water-resistance of samples was enhanced.therefore the samples could be easily molded.But the compressive strength of the bone cement decreased a little.The pH value of the hydrated bone cement increased gradually with time and was close to the pH value of physiological saline at hour 24.The compressive strength of bone cement was achieyed at 24 hours and it almost did not change after 48 hours.the drawback of ceramic HA,including sintering and difficulties in shaping.It has the characteristics of simple-producing,easy application and low heat energy.