中南大学学报(医学版)
中南大學學報(醫學版)
중남대학학보(의학판)
JOURNAL OF CENTRAL SOUTH UNIVERSITY (MEDICAL SCIENCES)
2011年
8期
739-743
,共5页
张尧%王鹏%马子龙%徐再峰%李毅
張堯%王鵬%馬子龍%徐再峰%李毅
장요%왕붕%마자룡%서재봉%리의
性功能%美沙酮维持治疗%男性成瘾者
性功能%美沙酮維持治療%男性成癮者
성공능%미사동유지치료%남성성은자
sexual function%methadone maintenance therapy%male addict
目的:调查社区美沙酮维持治疗门诊男性病人性功能状况,分析其原因并探讨对策.方法:使用自制性功能状况调查表和勃起功能国际问卷-5对612名患者进行调查.结果:接受美沙酮维持治疗后性生活主观感受变差的患者要显著多于主观感受良好的患者(P<0.01),88.6%的患者不满意当前性生活状况,但90.7%的患者愿意继续接受美沙酮维持治疗;性欲低下患者和勃起功能障碍患者要多于接受治疗前(P<0.01);性功能正常患者和射精受抑患者要少于治疗前(P<0.0l);勃起功能国际问卷-5评分与接受治疗时间无相关性,而与美沙酮维持剂量、患者年龄呈负相关.结论:美沙酮对男性性功能存在影响,适当的美沙酮维持剂量可以减少此类影响并提高治疗依从性.
目的:調查社區美沙酮維持治療門診男性病人性功能狀況,分析其原因併探討對策.方法:使用自製性功能狀況調查錶和勃起功能國際問捲-5對612名患者進行調查.結果:接受美沙酮維持治療後性生活主觀感受變差的患者要顯著多于主觀感受良好的患者(P<0.01),88.6%的患者不滿意噹前性生活狀況,但90.7%的患者願意繼續接受美沙酮維持治療;性欲低下患者和勃起功能障礙患者要多于接受治療前(P<0.01);性功能正常患者和射精受抑患者要少于治療前(P<0.0l);勃起功能國際問捲-5評分與接受治療時間無相關性,而與美沙酮維持劑量、患者年齡呈負相關.結論:美沙酮對男性性功能存在影響,適噹的美沙酮維持劑量可以減少此類影響併提高治療依從性.
목적:조사사구미사동유지치료문진남성병인성공능상황,분석기원인병탐토대책.방법:사용자제성공능상황조사표화발기공능국제문권-5대612명환자진행조사.결과:접수미사동유지치료후성생활주관감수변차적환자요현저다우주관감수량호적환자(P<0.01),88.6%적환자불만의당전성생활상황,단90.7%적환자원의계속접수미사동유지치료;성욕저하환자화발기공능장애환자요다우접수치료전(P<0.01);성공능정상환자화사정수억환자요소우치료전(P<0.0l);발기공능국제문권-5평분여접수치료시간무상관성,이여미사동유지제량、환자년령정부상관.결론:미사동대남성성공능존재영향,괄당적미사동유지제량가이감소차류영향병제고치료의종성.
Objective To determine sexual function in 612 male addicts with methadone maintenance therapy (MMT),analyze its cause and explore the treatment strategies.Methods Self-made questionnaire and International Index of Erectile Function-5 ( IIEF-5 ) were used in 612male addicts receiving MMT.Results The number of addicts who felt worse sexual function was significantly more than those who felt better sexual function (P <0.01 ).About 88.6% addicts were dissatisfied with their current sexual function,90.7% of whom were willing to continuously receive MMT.The number of addicts suffering from hyposexuality and erectile dysfunction (ED) was significantly increased at post-MMT than at pre-MMT ( P < 0.01 ),while the number of addicts with normal sexuality and inhibitive ejaculation decreased significantly (P <0.01 ).Both the dose of methadone and the age of subjects were negatively correlated with IIEF-5 scores.Correlation between the duration of MMT and IIEF-5 scores was not found.Conclusion MMT might deteriorate sexual function in male addicts.To improve the compliance of MMT and sexual function in male addicts,the dose of methadone should be adjusted to minimally effective one.