中华心律失常学杂志
中華心律失常學雜誌
중화심률실상학잡지
CHINESE JOURNAL OF CARDIAC ARRHYTHMIAS
2011年
2期
128-131
,共4页
谭团团%于胜波%包明威%陈葵%葛健%左进%胡曙萍%周纪宁%杨剑雪%王芳%哈飞
譚糰糰%于勝波%包明威%陳葵%葛健%左進%鬍曙萍%週紀寧%楊劍雪%王芳%哈飛
담단단%우성파%포명위%진규%갈건%좌진%호서평%주기저%양검설%왕방%합비
QT间期%心力衰竭%心脏性猝死%心律失常
QT間期%心力衰竭%心髒性猝死%心律失常
QT간기%심력쇠갈%심장성졸사%심률실상
QT Interval%Heart failure%Sudden cardiac death%Arrhythmias
目的 探索慢性心力衰竭患者QT间期频率依赖性与室性心律失常的关系.方法 选31例慢性心力衰竭患者有效病例资料.检测左心窜舒张末期内径(LVEDD)、左心室射血分数(LVEF)、QT间期离散度(QTd)、心率变异性(HRV)、QT/RR相关直线的斜率、24 h室性早搏(VPB)和非持续性室性心动过速(NSVT)的次数.比较有NSVT和无NSVT患者上述指标的差别,研究上述指标与NSVT的相关性.结果 31例心力衰竭患者中,有17例动态心电图记录到NSVT.有NSVT与无NSVT的患者比较,VPB次数[(5631.2±7218.0)对(285.9±371.7),P<0.05],QTe/RR斜率[(0.210±0.049)对(0.161±0.058),P<0.05]和QTp/RR斜率[(0.195±0.046)对(0.151±0.041),P<0.05]的差异有统计学意义.在全部31例患者中,QTd(r=0.414)、VPB次数(r=0.768)、QTe/RR斜率(r=0.380)、QTp/RR斜率(r=0.433)和NSVT有显著的相关性(P<0.05).结论 QT间期频率依赖性是反映QT间期动态变化的指标,慢性心力衰竭患者的QT/RR斜率与室性心律失常有较好的相关性,在心脏性猝死的风险评估中有一定价值.
目的 探索慢性心力衰竭患者QT間期頻率依賴性與室性心律失常的關繫.方法 選31例慢性心力衰竭患者有效病例資料.檢測左心竄舒張末期內徑(LVEDD)、左心室射血分數(LVEF)、QT間期離散度(QTd)、心率變異性(HRV)、QT/RR相關直線的斜率、24 h室性早搏(VPB)和非持續性室性心動過速(NSVT)的次數.比較有NSVT和無NSVT患者上述指標的差彆,研究上述指標與NSVT的相關性.結果 31例心力衰竭患者中,有17例動態心電圖記錄到NSVT.有NSVT與無NSVT的患者比較,VPB次數[(5631.2±7218.0)對(285.9±371.7),P<0.05],QTe/RR斜率[(0.210±0.049)對(0.161±0.058),P<0.05]和QTp/RR斜率[(0.195±0.046)對(0.151±0.041),P<0.05]的差異有統計學意義.在全部31例患者中,QTd(r=0.414)、VPB次數(r=0.768)、QTe/RR斜率(r=0.380)、QTp/RR斜率(r=0.433)和NSVT有顯著的相關性(P<0.05).結論 QT間期頻率依賴性是反映QT間期動態變化的指標,慢性心力衰竭患者的QT/RR斜率與室性心律失常有較好的相關性,在心髒性猝死的風險評估中有一定價值.
목적 탐색만성심력쇠갈환자QT간기빈솔의뢰성여실성심률실상적관계.방법 선31례만성심력쇠갈환자유효병례자료.검측좌심찬서장말기내경(LVEDD)、좌심실사혈분수(LVEF)、QT간기리산도(QTd)、심솔변이성(HRV)、QT/RR상관직선적사솔、24 h실성조박(VPB)화비지속성실성심동과속(NSVT)적차수.비교유NSVT화무NSVT환자상술지표적차별,연구상술지표여NSVT적상관성.결과 31례심력쇠갈환자중,유17례동태심전도기록도NSVT.유NSVT여무NSVT적환자비교,VPB차수[(5631.2±7218.0)대(285.9±371.7),P<0.05],QTe/RR사솔[(0.210±0.049)대(0.161±0.058),P<0.05]화QTp/RR사솔[(0.195±0.046)대(0.151±0.041),P<0.05]적차이유통계학의의.재전부31례환자중,QTd(r=0.414)、VPB차수(r=0.768)、QTe/RR사솔(r=0.380)、QTp/RR사솔(r=0.433)화NSVT유현저적상관성(P<0.05).결론 QT간기빈솔의뢰성시반영QT간기동태변화적지표,만성심력쇠갈환자적QT/RR사솔여실성심률실상유교호적상관성,재심장성졸사적풍험평고중유일정개치.
Objective To investigate the relationship between QT interval rate dependence and ventricular arrhythmias in patients with chronic heart failure.Methods Thirty-one patients with chronic heart failure were enrolled in this study and investigation included history collection,clinical examination,echocardiography,electrocardiogram and 24h ambulatory electrocardiogram.Following indexes were determined,left ventricular end diastolic dimension(LVEDD),left ventricular ejection fraction(LVEF),QT dispersion(QTd),SDNN.the slope of QT/RR plots of the linear regression,ventricular premature beats(VPB)and non-sustained ventricular tachycardia(NSVT).All above indexes were compared between patients with and without NSVT,The correlation factor between QT/RR slope and NSVT was calculated.Results In 31 patients with chronic heart failure.there were 17 patients with NSVT in their 24 h holter recording.The frequency of VPB(5631.2±7218.0 vs 285.9±371.7,P<0.05),QTe/RR slope(0.210±0.049 vs 0.161±0.058,P<0.05)and QTp/RR slope(0.195±0.046 vs 0.151±0.041,P<0.05)were significantly higher in patients with NSVT than those without.In all patients,QTd(r=0.414,P<0.05),VPB(r=0.768,P<0.05),QTe/RR slope(r=0.380.P<0.05)and QTp/RR slope(r=0.433,P<0.05)highly correlated to the frequency of NSVT.Conclusion QT interval rate dependence represents the dynamic QT variance over time.QT/RR slope correlates to the ventricular arrhythmia tightly,and is valuable fbr the risk stratification of sudden cardiac death in chronic hean failure.
