中国临床保健杂志
中國臨床保健雜誌
중국림상보건잡지
CHINESE JOURNAL OF CLINICAL HEALTHCARE
2009年
3期
256-257
,共2页
王弋%孙杭临%胡芝%叶琼%叶枫
王弋%孫杭臨%鬍芝%葉瓊%葉楓
왕익%손항림%호지%협경%협풍
卵巢肿瘤%内皮素-1%免疫组织化学%危险因素
卵巢腫瘤%內皮素-1%免疫組織化學%危險因素
란소종류%내피소-1%면역조직화학%위험인소
Ovarian neoplasms%Endothelin-1%Immunohistochemistry%Risk factors
目的 探讨内皮素-1(ET-1)在卵巢肿瘤组织中的表达和临床意义.方法 应用免疫组织化学法检测56份卵巢癌,19份良性卵巢肿瘤和17份正常卵巢组织中ET-1的表达.结果 ET-1在卵巢肿瘤中的表达明显高于正常卵巢组织(P<0.05),在卵巢癌中的表达明显高于卵巢良性肿瘤(P<0.05),但和卵巢癌的病理类型及病理分级、临床分期无关(P>0.05).结论 ET-1和卵巢肿瘤的发生有关系.
目的 探討內皮素-1(ET-1)在卵巢腫瘤組織中的錶達和臨床意義.方法 應用免疫組織化學法檢測56份卵巢癌,19份良性卵巢腫瘤和17份正常卵巢組織中ET-1的錶達.結果 ET-1在卵巢腫瘤中的錶達明顯高于正常卵巢組織(P<0.05),在卵巢癌中的錶達明顯高于卵巢良性腫瘤(P<0.05),但和卵巢癌的病理類型及病理分級、臨床分期無關(P>0.05).結論 ET-1和卵巢腫瘤的髮生有關繫.
목적 탐토내피소-1(ET-1)재란소종류조직중적표체화림상의의.방법 응용면역조직화학법검측56빈란소암,19빈량성란소종류화17빈정상란소조직중ET-1적표체.결과 ET-1재란소종류중적표체명현고우정상란소조직(P<0.05),재란소암중적표체명현고우란소량성종류(P<0.05),단화란소암적병리류형급병리분급、림상분기무관(P>0.05).결론 ET-1화란소종류적발생유관계.
Objective To investigate the expression of endothelin-1(ET-1) in ovarian tumors.Methods Expression of ET-1 in ovarian tumors(malignant n=56 benign tumor n=19,normal tissue n=17) was evaluated by immunohistochemical staining.Results Expression of ET-1 in ovarian tumors was significantly higher than that in normal tissues(P<0.05),Expression of ET-1 in ovarian cancers was significantly higher than that in benign tumors(P<0.05).However,ET-1 expression was not correlated with different histological classifications (P>0.05),differentiation grade(P>0.05) and International Federation of Gynecololgy and Obstetrics(FIGO) stage (P>0.05),Conclusion The results indicate that ET-1 plays some role in occurrence of the ovarian tumors.
