化学通报（印刷版）
化學通報（印刷版）
화학통보（인쇄판）
CHEMISTRY
2010年
4期
314-325
,共12页
喹唑啉%合成方法%生物活性
喹唑啉%閤成方法%生物活性
규서람%합성방법%생물활성
Quinazolines%Synthesis%Biological activities
喹唑啉类化合物在药物和农药领域具有多种优良的生物和生理活性,其合成方法是目前药物和农药研究的热点领域之一.本文着重从构筑喹唑啉母环骨架的角度出发,按成环原料种类对喹唑啉环的构筑和喹唑啉类化合物的合成方法和研究进展作一综述.同时对喹唑啉类化合物在抗肿瘤、抗疟、抗菌、抗病毒等方面的生物活性进行了介绍.
喹唑啉類化閤物在藥物和農藥領域具有多種優良的生物和生理活性,其閤成方法是目前藥物和農藥研究的熱點領域之一.本文著重從構築喹唑啉母環骨架的角度齣髮,按成環原料種類對喹唑啉環的構築和喹唑啉類化閤物的閤成方法和研究進展作一綜述.同時對喹唑啉類化閤物在抗腫瘤、抗瘧、抗菌、抗病毒等方麵的生物活性進行瞭介紹.
규서람류화합물재약물화농약영역구유다충우량적생물화생리활성,기합성방법시목전약물화농약연구적열점영역지일.본문착중종구축규서람모배골가적각도출발,안성배원료충류대규서람배적구축화규서람류화합물적합성방법화연구진전작일종술.동시대규서람류화합물재항종류、항학、항균、항병독등방면적생물활성진행료개소.
Quinazolines have shown many excellent biological activities both in the areas of medicine and pesticide.Their synthetic methods are important topics of pharmaceutical and pesticidal researches at present.The progress of synthetic methods of quinazolines has been reviewed from the point of building the ring skeleton and based on the types of raw materials.At the same time,the biological activities of quinazolines such as the anti-tumor,anti-malarial,antibacterial,antiviral and so on have been introduced.
