CAJ | 학술논문

目的探讨嗅觉事件相关电位(olfactory event related potentials,OERP)和嗅觉通路MRI对外伤后失嗅的评估价值.方法回顾性分析24例外伤后失嗅患者的临床资料.所有患者均行详细的病史采集、全面体检、T&T嗅觉检查、鼻内镜检查、OERP测试、颅脑CT和嗅觉通路MRI检查.结果主观嗅觉测试:双侧完全失嗅20例;单侧完全失嗅,对侧嗅觉减退2例;单侧完全失嗅,对侧嗅觉正常2例.OERP测试:双侧最大嗅刺激均不能引出OERP者20例,单侧最大嗅刺激不能引出OERP者4例;单侧能引出OERP者4例,其中2例能正常引出,另2例OERP幅值下降且潜伏期延长.氨气刺激均能引出鼻内三叉神经化学感受事件相关电位.嗅路MRI检查:嗅球损伤24例次(100%),额叶直回损伤22例次(91.7%),额叶眶回损伤16例次(67%),远端嗅束和颞叶损伤各2例次(8%).结论 OERP能对外伤后嗅觉进行定性和定量的客观整体评估;嗅路MRI能对外伤后失嗅的损伤部位、程度进行客观、精确的评估.两者结合能对嗅觉功能进行全面、客观评价.
목적 탐토후각사건상관전위(olfactory event related potentials,OERP)화후각통로MRI대외상후실후적평고개치.방법 회고성분석24예외상후실후환자적림상자료.소유환자균행상세적병사채집、전면체검、T&T후각검사、비내경검사、OERP측시、로뇌CT화후각통로MRI검사.결과 주관후각측시:쌍측완전실후20례;단측완전실후,대측후각감퇴2례;단측완전실후,대측후각정상2례.OERP측시:쌍측최대후자격균불능인출OERP자20례,단측최대후자격불능인출OERP자4례;단측능인출OERP자4례,기중2례능정상인출,령2례OERP폭치하강차잠복기연장.안기자격균능인출비내삼차신경화학감수사건상관전위.후로MRI검사:후구손상24례차(100%),액협직회손상22례차(91.7%),액협광회손상16례차(67%),원단후속화섭협손상각2례차(8%).결론 OERP능대외상후후각진행정성화정량적객관정체평고;후로MRI능대외상후실후적손상부위、정도진행객관、정학적평고.량자결합능대후각공능진행전면、객관평개.
Objective Using olfactory event related potentials(OERP) and magnetic resonance to evaluate olfactory function in patients with posttraumatic anosmia. Methods Twenty four patients with posttraumatic anosmia were reviewed retrospectively. A thorough medical history,physical examination,nasal endoscopy,T&T olfactory testing,olfactory event-related potentials,brain computed tomography scan and magnetic resonance image of olfactory pathway were performed in all patients. Results Subjective olfactory testing indicated 20 of 24 patients were birhinal anosmia. 2 with right nostril anosmia and left impairment,2 with left anosmia and right normal. No OERP were obtained in 24(20 were birhinal,4 was monorhinal),except 4 cases with single nostril. Magnetic resonance imaging revealed the injures to the olfactory bulbs(100%),rectus gyrus(91.7%),orbital gyrus(67%),olfactory tracts(8%) and temporal lobes(8%). Conclusions OERP can objectively evaluate posttraumatic olfactory function,and magnetic resonance of olfactory pathway can precisely identify the location and extent of injures.